Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"PTGS"”.
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The Role of Maelstrom in the Drosophila piRNA Pathway
… (TGS) and post-transcriptional gene silencing (PTGS) pathways. The role of Maelstrom in TGS is investigated in the first chapter and specifically its involvement in the Piwi-dependent silencing machinery that represses transposons by modifying chromatin. Maelstrom plays an important role in this …
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Studio dei meccanismi molecolari coinvolti nel determinismo sintomatologico di piante infette da virus e virus-satelliti
… to plant post transcriptional gene silencing (PTGS) mechanism. In our case, inoculation of N. benthamiana plants transformed with another PTGS viral suppressor (p19), and other plants defective for RNA polymerase 6 (involved in systemic silencing), still resulted in yellowing appearance. This, …
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Molecular and Genetic Analysis of Novel Epigenetic Silencing Factors Dhp1, Lsd1, and Lsd2
… as a post-transcriptional gene silencing (PTGS) mechanism independently of previously identified PTGS mechanisms. In the third chapter, we attempt to elaborate on the mechanism of Dhp1-mediated silencing via genetic analysis of Dhp1-interacting proteins but are unable to identify a simple …
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Soybean Mosaic Virus Hc-Pro Enhances Viral Symptoms, Bean Pod Mottle Virus and Transgene RNA Stability, siRNA Accumulation, and Reduces Soybean Seed Production
… RNA by post-transcriptional gene silencing (PTGS), which is characterized by the accumulation of small interfering RNAs (siRNAs). In soybean plants infected with BPMV alone, siRNA accumulation was correlated with accumulation of BPMV genomic RNAs, but siRNA were not detected in plants that …
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Impact des microvésicules de plaquettes sur l'expression de produits inflammatoires des monocytes et macrophages THP-1
… protéines des gènes prostaglandine synthases (PTGS) 1 et 2, lipoxygénases (ALOX) 5, 12 et 15, et thromboxane A synthase 1 (TBXASI) ont été quantifiés par la méthode rétrotranscription-réaction de polymérase en chaine quantitative (RT-qPCR) et immunobuvardage de type western, respectivement. …
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Synthesis, Characterization, and Evaluation of Amphiphilic Cell-Penetrating Peptides as siRNA Delivery Tools for Cancer Therapy
<p>Post-transcriptional gene silencing (PTGS), also termed as RNA interference (RNAi) possess a great therapeutic potential. Three siRNA-based products have been recently approved that have developed a renewed interest in the scientific community to explore this alternative therapeutic area …
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Function and Regulation of Xylem Cysteine Protease 1 and Xylem Cysteine Protease 2 in Arabidopsis
A functional water-conducting system, the tracheary elements of the xylem, is required to sustain plant growth and development. Tracheary element formation is dependent on many biological processes terminated by programmed cell death and cellular autolysis. The final two processes are probably …
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Small non-coding RNA-mediated epigenetic regulation of gene expression and its implications for wheat adaptation to continuous cultivation
Winter wheat (Triticum aestivum L.) is one of the most important staple crops worldwide. However, continuous wheat cultivation often leads to yield decline which poses a serious threat to sustainable wheat production. This yield decline is generally attributed to the interaction of abiotic and …