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Showing 1 to 20 of 74 for “"PTB"”.
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Unique Features of PTB RRMs: Insight into Protein Motions and RNA Binding
Polypyrimidine tract binding protein: PTB) is a highly conserved RNA binding protein comprised of four RRMs: RNA recognition motifs). RRMs are extremely prevalent in all kingdoms of life, and have been very well characterized in terms of structure and RNA binding properties. However, all four RRMs …
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A study of pharmacokinetics of anti tuberculosis drugs in Zambian PTB patients co-infected with the Human Immuno-Deficiency Virus
… isoniazid and pyrazinamide in Zambian PTB patients with HIV at the University Teaching Hospital, Lusaka, Zambia. The assaying of the drugs was done at the University College London Medical School.To determine whether the pharmacokinetics of anti-tuberculosis drugs at steady-state are …
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Posttraumatische Belastungsstörungen und andere psychische Störungen nach schweren Verkehrs- und Arbeitsunfällen : eine prospektive Studie
… zum gegenwärtigen Stand der Erforschung der PTB und anderer psychischer Störungen nach traumatischen Ereignissen wird deutlich, dass es über das Auftreten dieser Erkrankung in Folge von Verkehrs- und Arbeitsunfällen bisher nur wenig gesicherte Erkenntnisse gibt. <br> <br>293 …
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Longitudinal changes in clinical symptoms and signs in children with confirmed, unconfirmed, and unlikely pulmonary tuberculosis
… nature of paediatric pulmonary tuberculosis (PTB) makes microbiological diagnosis difficult and limits the usefulness of microbiology for assessing treatment efficacy. Clinical response to treatment has thus been used by clinicians to monitor disease activity, as well as by researchers in …
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Assessment of airway compression on chest radiographs in children with pulmonary tuberculosis
… rationale: Diagnosis of pulmonary tuberculosis (PTB) in children relies heavily on chest radiography as sputum samples are difficult to obtain and only yield positive results in 30-74% of children treated for PTB. However, radiological signs between lower respiratory tract infections (LRTI) and …
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Knowledge of the Students Regarding Pulmonary Tuberculosis at a Selected Tertiary Institution in Vhembe District of Limpopo Province
… Social Sciences (SPSS). Pulmonary Tuberculosis (PTB) knowledge was assessed and analysed using a self-administered questionnaire. A Spearman’s rank-order correlation was run to determine the relationship between the education and the knowledge of TB among the respondents. Results: The results of …
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Membrane binding properties of Disabled-2
… endocytosis, the Dab2 phosphotyrosine-binding (PTB) domain mediates protein binding to phosphatidylinositol 4,5-bisphosphate (PIP2) at the inner leaflet of the plasma membrane and helps co-localization with clathrin coats. Dab2, released from platelet alpha granules, inhibits platelet …
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Inflammatory response in maternal serum during preterm labour
Preterm birth (PTB), defined as a delivery at less than 37 weeks of gestation, is the leading cause of perinatal morbidity and mortality worldwide. The serious effects of PTB on parents, infant and society make PTB an important issue to public health. Despite significant advances in perinatal care …
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The effect of a community based pulmonary rehabilitation programme on the quality of life of patients with pulmonary tuberculosis
… patients diagnosed with Pulmonary Tuberculosis (PTB). The prevalence of PTB in South Africa is one of the highest in the African continent. Assessing the effectiveness of the programme could provide further methods in improving compliance to pharmaceutical medication as well as an improvement in …
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The prevalence of Mycobacterium Tuberculosis in patients with a short history of cough (less than three weeks) at Kamwala, Chilenje and Kabwata Clinics, Lusaka, Zambia
… Aim: The prevalence of pulmonary tuberculosis (PTB) in patients with a short duration of cough was determined at 3 urban clinics of Lusaka. Hypothesis: A significant proportion of patients with pulmonary tuberculosis present with cough less than 3 weeks duration. Methodology: Two hundred and …
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The prevalence of Mycobacterium Tuberculosis in patients with a short history of cough (less than three weeks) at Kamwala, Chilenje and Kabwata Clinics, Lusaka, Zambia
… Aim: The prevalence of pulmonary tuberculosis (PTB) in patients with a short duration of cough was determined at 3 urban clinics of Lusaka. Hypothesis: A significant proportion of patients with pulmonary tuberculosis present with cough less than 3 weeks duration. Methodology: Two hundred and …
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Perinatal Depression and Preterm Birth
… notable 15 year low in overall preterm birth (PTB), a 10% improvement since the 2006 peak with declines for each of the largest race and Hispanic origin groups, the United States has the highest rate of PTB of any industrialized country with estimates of 11.5% or approximately 500,000 infants …
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Protein/Peptide Recognition Modules in Cellular Signaling and HIV Pathogenesis
… domains: SH2 (Src homology 2) domains, PTB (phosphotyrosine binding) domains, and SH3 (Src homology 3) domains. The SH2 domains recognize tyrosylphosphorylated peptides using a binding mode that is conserved among the SH2 family members. In particular, the structure of the SH-PTP2 SH2 …
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Disabled-2 regulates platelet heterotypic and homotypic aggregation through sulfatide binding
… Dab2 binds to the αIIbβ3 integrin, through the PTB domain, and blocks fibrin binding to the integrin which serves as the major cause of platelet-platelet interactions. Dab2 is also capable of binding to sulfatides, through the N-PTB region, expressed on the outer leaflet of adjacent cells. …
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Pulmonary Tuberculosis: towards improved adjunctive therapies
The potential to improve pulmonary tuberculosis (PTB) treatment outcomes with adjunctive immunotherapies requires investigation. L-arginine and vitamin D have antimycobacterial properties which render them suitable candidates. Therefore the Arginine and Vitamin D Adjunctive therapy in Pulmonary TB …
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Pulmonary Tuberculosis: towards improved adjunctive therapies
The potential to improve pulmonary tuberculosis (PTB) treatment outcomes with adjunctive immunotherapies requires investigation. L-arginine and vitamin D have antimycobacterial properties which render them suitable candidates. Therefore the Arginine and Vitamin D Adjunctive therapy in Pulmonary TB …
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A descriptive study of IgG subclasses and allotypes in children with pulmonary tuberculosis in the Western Cape
… in children with pulmonary Tuberculosis (PTB) in the Western Cape. DESIGN: Consecutive children under 15 years of age with microbiological proven PTB over an 8 month period- November 1993 to July 1994. SETTING: Teaching Hospitals in Cape Town. PATIENTS: Thirty-five cases were selected from …
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The Role Of Chronic Stress In Age Gradients Of Preterm Birth Among Racial/ethnic Groups
… as an underlying mechanism of preterm birth (PTB) among racial/ethnic minority women. However, the association between chronic stress and PTB is not clearly understood. In fact, existing chronic stress models do not agree on definitions and assessments of chronic stress, rarely reflect …
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Sulfatides mediate Disabled-2 membrane localization and stability during platelet aggregation
… aggregation through its phosphotyrosine-binding (PTB) domain by competing with fibrinogen for ï ¡IIï ¢3 integrin binding on the activated platelet surface.3 Sulfatides are also found on the platelet surface,4 interacting with adhesive and coagulation proteins5-7 and, thus, they are thought to play …
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Identification and validation of biomarkers for early diagnosis and resilience to bovine paratuberculosis using proteomics and immunohistochemical approaches
La Paratuberculosis bovina (PTB) es una enteritis granulomatosa crónica, causada por Mycobacterium avium subsp. paratuberculosis (Map), que afecta principalmente a los rumiantes. Esta enfermedad es especialmente relevante en regiones ganaderas, como Asturias (norte de España), debido a su impacto …
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