Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"PSIP1"”.
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Investigating the role of HOTTIP, HOXA13 and PSIP1 in cancer.
… and HOXA genes are regulated by the oncogenic PSIP1 protein. Using both siRNA mediated knockdown and CRISPR-Cas9 mediated genetic knockout approaches, the role of HOTTIP, HOXA13 and PSIP1 were investigated in both CRC and PCa. Through loss of function studies, depletion of HOTTIP, HOXA13 and …
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Investigating the transcriptional regulation of BCL11A in Triple-negative Breast Cancer
… led to the identification of DEK, SSRP1 and PSIP1 as potential regulators of BCL11A’s expression. Experimentally, I found knocking- down DEK, SSRP1 and PSIP1 resulted in a reduction in BCL11A’s expression in TNBC. These results highlight a novel approach for the identification of …