Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"PP2B"”.
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Role of vascular smooth muscle Interleukin-11 in aortic aneurysm development
… the calcium-dependent phosphatase calcineurin (PP2B). PP2B then dephosphorylates the inactive, phosphorylated nuclear factor of activated T-cells (NFAT), facilitating the activation and nuclear translocation of NFAT2, which may promote IL-11 transcription. Western blot analysis was performed to …
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Molecular mechanisms of synaptic plasticity
… inhibits the expression of LTP via regulating PP2B activity. We have also found that neurogranin interferes with calcium-dependent inactivation of neuronal L-type calcium channels and allows a sustained influx of calcium during the membrane depolarization in hippocampal neurons. Our results …
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Purification and characterization of a protein phosphatase (PP1-Arch) from the archaebacterium Sulfolobus solfataricus, isolation and expression of its gene
… sequence homology between PP1-Arch and PP1/PP2A/PP2B suggests that they belongs to the same genetic family. A recombinant plasmid which was derived from pT7-7 was constructed for expression of PP1-Arch. The PP1-Arch gene was expressed in <i>E. coli</i> and the activity of the expressed enzyme was …
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Design and Development of a Novel Immunological Method to Quantify target-specific cysteine redox state in a microplate
… (PTEN), cγ subunit of protein phosphatase 2B (PP2B) and<br/>the bulk thiol pool. These findings provide further insight into the redox regulation<br/>of endotoxin signalling and showcase the various advantages of RedoxiFluor.
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Molecular Characterization of Dopamine Transporter Phosphorylation and Regulation
… of NDAT. Protein phosphatases (PP1 and PP2B) were able to dephosphorylate the PKCα phosphorylated NDAT; however, none of the tested protein phosphatases were able to dephosphorylate the ERK1 phosphorylated NDAT. Further, we have identified T53 as a MAPK phosphorylation site on NDAT …
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Unraveling the Dynamics of Ser126 Phosphorylation in Paxillin: A Focus on Phosphatase Activity
Paxillin is a focal adhesion adaptor protein essential for cell adhesion and migration, regulated by reversible phosphorylation. In endothelial cells, phosphorylation at serine 126 (Ser126) plays a key role in processes like angiogenesis and vascular permeability. This study aimed to identify the …