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Showing 1 to 3 of 3 for “"PP1 phosphatase"”.
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Differential Regulation of Phosphatidylinositol 4-Phosphate 5 Kinase Beta during Hypertonic and Oxidative Stress
… Hypertonic stress activates PIP5Kbeta through PP1 phosphatase dependent ser/thr dephosphorylation which leads to increased kinase activity and plasma membrane localization. The PIP2 produced by PIP5Kbeta during this event leads to an increase in actin polymerization and stress fiber formation. …
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Role of phosphatases in the end-on conversion process
… unknown. This project aimed to study the role of phosphatases in the regulation of the end-on conversion process. First, I investigated the different contribution of the two outer-kinetochore phosphatases - BubR1- recruited PP2A-B56 and KNL1-recruited PP1 - in counteracting Aurora B kinase during …
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Analysis of the functions of phosphoprotein phosphatase 1 catalytic subunits during cell division
… proteins. One of the most abundant families of phosphatases in the eukaryotic cell is the phosphoprotein phosphatase 1 (PP1) family of phosphatases. These phosphatases are holoenzymes composed of one of three catalytic subunits -α, β, and γ - in complex with one or two regulatory subunits. There …