Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"POLYMYXINS"”.
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Liposomes as carriers for polymyxins in the treatment of cystic fibrosis lung infections
… Recently, attention has focused on aerosolised polymyxins, which are given prophylactically in an effort to limit infection and subsequent lung damage. This class of antimicrobial compounds is highly active against P. aeruginosa and possess the advantage that resistance rarely develops. However, …
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Stress And Survival Of Enterobacteriaceae: Studies Of Dehydration Tolerance And Polymyxin Resistance
… how Enterobacteriaceae adapt to dehydration and polymyxins. Dehydration is an environmental stress that many bacteria encounter in their ecological niches. However, the mechanisms involved in surviving dehydration are not well understood, particularly in Gram-negative bacteria. In Chapter 2 we …
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ΕΠΙΔΡΑΣΗ ΤΩΝ ΑΜΙΝΩΝ ΣΤΙΣ ΔΟΜΙΚΕΣ ΚΑΙ ΚΑΤΑΛΥΤΙΚΕΣ ΙΔΙΟΤΗΤΕΣ ΤΗΣ ΓΛΥΚΟΓΟΝΙΚΗΣ ΦΩΣΦΟΡΥΛΑΣΗΣ Β
… THE ALIPHATIC AMINES, THE PHENOTHIAZINES AND THE POLYMYXINS. THESE AMINES IN THE PRESENCE OF AMP INDUCE A SIGNIFICANT ENHANCEMENT OF ENZYME ACTIVITY. THE BINDING CENTER OF PHOSPHORYLASE B FOR AMINES IS POSSIBLY LOCATED ON THE N-TERMINAL CHAIN OF PHOSPHORYLASE B. FROM ALL AMINES, POLYMYXIN B IS THE …
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Chemical Synthesis of Novel Calcium-Dependent Lipopeptide Antibiotics
… antibiotics and include clinically important polymyxins and vancomycin used for the treatment of multi-drug resistant (MDR) infections. An important class of AMPs are calcium-dependent lipopeptide antibiotics (CDLAs) of which daptomycin is the only novel antibiotic introduced for clinical use …
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Elucidation of the Molecular Mechanisms That Contribute to Variation in Susceptibility Testing Show the Need for Alternative Detection Methods of KPC-producing Gram-negative Bacteria
… antibiotics, such as the aminoglycosides and polymyxins. The rapid spread of blaKPC into multiple genera of Gram-negative bacteria, the lack of effective treatment regimens, and the difficulty of identifying these pathogens using current detection methods in the clinical laboratories are the …