Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"PNPLA2"”.
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Functional validation of human rare missense variants associated with body fat distribution and cardiometabolic risk
… cardiometabolic disease, while a variant in gene PNPLA2 (p.N252K) was associated with an adverse phenotype (1). To understand the roles of these genes, initial loss-of-function studies were carried out using siRNA-mediated knockdown in 3T3-L1 (pre)adipocytes, as all the genes are expressed in …
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Transition cows: hepatic endocannabinoid system gene expression in response to prepartal plane of nutrition and the effects of genetic merit on genes of lipid metabolism in adipose tissue
… in lipolysis; classical lipolytic geness (LIPE, PNPLA2, MGLL, ADRB2, ADFP, ABHD5), genes controlling lipolysis (INSR, AKT1, PDE3A, PDE3B, PRKAA1, PRKAA2, FOXO1, SIRT1), and other proteins (GHR, CAV1, ADIPOQ, TNF1) was also measured. Dry matter intake, blood glucose and NEFA were not significantly …
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Regulation of Systemic and Cellular Metabolism In Prostate Cancer By Camkk2 and Elucidation of Atgl’S Role In Disease Progression
<p>The androgen receptor (AR) is the major driver of prostate cancer; hence, men with progressing disease are treated with androgen deprivation therapy (ADT). However, the majority of patients will relapse within 2-3 years due to multiple AR reactivation mechanisms. Thus, AR and the processes …