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Showing 1 to 20 of 46 for “"PNIPAM"”.
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Topographically and Mechanically Tunable PNIPAM Scaffolds
Poly(N-isopropyl-acrylamide) (PNIPAM) is a thermoresponsive polymer with a wide range of biological applications, including drug delivery, biosensing, and tissue engineering. The tunability of the structural and mechanical properties of PNIPAM makes it particularly at- tractive in emulating cell …
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Synthesis and study of the micellization behavior of a dual temperature- and pH-responsive PAA-b-PNIPAM block copolymer
… acid-block-N-isopropylacrylamide) (PAA-b-PNIPAM) diblock copolymers with different relative chain lengths of the hydrophobic and hydrophilic blocks were synthesized by reversible addition fragmentation chain transfer polymerization. The preliminary results showed high conversion values for …
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POLY(N-ISOPROPYL ACRYLAMIDE)-COATED SURFACES: INVESTIGATION OF CYTOTOXICITY WITH MAMMALIAN CELLS AND THE MECHANISM OF CELL DETACHMENT
… such material is poly(N-isopropyl acrylamide), (pNIPAM), which undergoes a conformation change in a physiologically relevant temperature range to release intact mammalian cell monolayers capable of being used to engineer tissues. Two factors currently limit the use of cell sheets for this …
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Advancing fast relaxation imaging to determine protein stability and folding kinetics on poly(n-isopropyl acrylamide) films
… the use of the thermo-responsive polymer PNIPAM to capture and release cells or proteins for medical purposes; however, this assumes that PNIPAM does not perturb the stability of biomolecules. Previous analytical and spectroscopic techniques have not been able to confirm this assumption …
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Enhancing microalgal biomass harvesting efficiency using thermoresponsive polymers
… biorefinery. Poly(N-isopropylacrylamide) (PNIPAM), known for its temperature-induced phase transition properties, is explored as a means to capture algal cells within the cultivation medium. This study investigates PNIPAM and its derivatives to elucidate the fundamental principles and …
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Synthesis and characterization of crystalline assembly of poly Nisopropylacry-lamide)-co-acrylic acid nanoparticles.
… poly(N-isopropylacrylamide-co-acrylic acid) (PNIPAm-co-AAc) nanoparticle network in organic solvents was obtained by self assembling precursor particles in acetone/epichlorohydrin mixture at room temperature followed by inter-sphere crosslinking at ~98 °C. The crystals thus formed can endure …
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Fabrication and light scattering study of multi-responsive nanostructured hydrogels and water-soluble polymers.
… acid (PAAc) and poly(N-isopropylacrylamide) (PNIPAM) interpenetrating networks were synthesized by 2-step method with first preparing PNIPAM microgel and then polymerizing acrylic acid that interpenetrates into the PNIPAM network. The semi-dilute aqueous solutions of the PNIPAM-PAAc IPN …
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Assessment of the biocompatibility, stability, and suitability of novel thermoresponsive films for the rapid generation of cellular constructs
… of an SRP is poly(N-isopropyl acrylamide) or pNIPAM. This SRP has the capability of changing its conformation with a slight temperature change: adherent mammalian cells spontaneously release as a confluent cell sheet, which can be harvested for cell sheet engineering purposes. Since its …
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Microscale actuators from carbon nanotube and hydrogel composites
… nanotubes (CNT) and poly(N-isopropylacrylamide) (PNIPAM) hydrogel, which have been combined to make a microactuator system with a wide range of possible designs without needing to modify the fabrication approach. These CNT/PNIPAM hydrogel microactuators have sizes ranging from 10 µm to 1 mm …
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Synthesis and study of crystalline hydrogels, guided by a phase diagram.
… of poly-N-isopropylacrylamide-co-allylamine (PNIPAM-co-allylamine) and PNIPAM-co-acrylic acid (AA) have been synthesized and used as building blocks for creating three-dimensional networks. The close-packed PNIPAM-co-allylamine and PNIPAM-co-AA nanoparticles were stabilized by covalently …
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Smart hybrid materials with tailored functions
… (PDMAEMA) and poly(N-isopropylacrylamid) (PNIPAM) Bürsten wurden mittels "Atom transfer radical polymerization" (ATRP) synthetisiert; die Beladung mit AuNPs erfolgte durch einen Inkubationsprozess. Beide Polymere weisen eine untere kritische Mischungstemperatur (LCST) auf, oberhalb derer …
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The synthesis and development of novel, easily processable poly (n-isopropylacrylamide)-based hyrdogels.
… a synthetic method which allows a fully-reacted PNIPAM/clay nanocomposite system to remain a watery liquid until it is cooled to a predetermined temperature. Beyond this temperature, the polymer/clay precursor hydrogel liquid (PCPH) spontaneously forms a cross-linked hydrogel that does not …
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Design, Synthesis and Characterisation of Amphiphilic Symmetrical triblock copolymers by the RAFT process : their self-organisation in dilute and concentrated aqueous solutions
… A blocks, poly(N-isopropylacrylamide) (PNIPAM) and poly(methoxy diethylene glycol acrylate) (PMDEGA) were employed, while as hydrophobic B blocks, poly(4-tert-butyl styrene), polystyrene, poly(3,5-dibromo benzyl acrylate), poly(2-ethylhexyl acrylate), and poly(octadecyl acrylate) were …
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An Injectable Thermosensitive Hydrogel Potentially Used for Wound Dressing with Self-adhesive Properties
… the local sites. Poly (N-Isopropylacrylamide) (PNIPAM) could be applied because PNIPAM-based polymers can achieve fast gelling at body temperature. Additionally, the introduction of dopamine could provide self-adhesive property for wound dressing applications because of possible bonds with …
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Development and Characterization of Reagent Pencils for Microfluidic Paper Based Analytical Devices
… responsive polymer, poly(N-isporopylacrylamide) (PNIPAM) was developed. In this work, PNIPAM’s lower critical solution temperature (LCST) was manipulated with various salt solutions to control fluid flow both laterally and vertically through various microPAD designs. It was found that, while …
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A Thermal Switch from Thermoresponsive Polymer Aqueous Solutions
… be expected. I used Poly(N-isopropylacrylamide) (PNIPAM) as an example to show the abrupt thermal conductivity change of thermoresponsive polymer solutions below and above their phase transition temperature. A novel technique, transition grating method, is used to measure the thermal conductivity. …
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Dynamic Plasmonic Systems with Actuating Nanotransducers
… coated with the poly(N-isopropylacrylamide) (PNIPAM). Gold nanoparticles have renowned tunable plasmonic properties, while PNIPAM is a well-known polymer that expands and contracts in response to temperature in aqueous media. The particular combination of these materials enables fast local …
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Introduction of a thermo-sensitive non-polar species into polyelectrolyte multilayer capsules for drug delivery
… active species. Poly-(N-isopropyl acrylamide), (PNIPAM) is known to be a thermo-sensitive polymer that has a Lower Critical Solution Temperature (LCST) around 32oC; above this temperature PNIPAM is insoluble in water and collapses. It is also known that with the addition of salt, the LCST …
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Synthesis of poly(NIPAM-co-vmbpy) microspheres and transition metal monomers for metallopolymeric material construction
<p>Poly-N-isopropylacrylamide (PNIPAM) gels grafted to redox-active metal monomers undergo sudden expansion-contraction activity in response to change in environmental conditions, such as temperature, pH, ion concentration, and oxidation states of the metal. The relevance of these conditions to …
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