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Showing 1 to 20 of 28 for “"PNIPAAm"”.
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Poly(N-Isopropylacrylamide)-based scaffolds for tissue engineering applications
… Poly(N-isopropylacrylamide), denoted PNIPAAm, is a synthetic polymer with hydrophilic properties at room temperature, but above 32C the chains become hydrophobic and entangle to form physical crosslinks. This thermoresponsive property enables PNIPAAm to be implanted as a free-flowing …
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Synthesis and characterization of tethered poly(n-isopropylacrylamide) for quantitative cell adhesion studies
… biofouling release. Poly(N-isopropylacrylamide) (PNIPAAm) is a thermo responsive polymer that can potentially be used to control biofouling, as it exhibits a change in its relative hydrophobicity above and below its lower critical solution temperature (LCST ~ 32\uf0b0C). This thesis reports on …
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Single molecule tracking studies of lower critical solution temperature transition behavior in poly(N-isopropylacrylamide)
… SMT, experiments in poly(n-isopropylacrylamide, pNIPAAm, were carried out using probe fluorophores that had partitioned into the polymer. When the pNIPAAm switches from expanded to collapsed at elevated temperatures, the free volume accessible to the diffusing molecules decreases and trajectories …
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Novel Precursors for Polymer-Protein-Conjugate Synthesis via Reversible Addition-Fragmentation Chain Transfer Polymerization
… construction of a calibration curve for PNIPAAm polymers. In-situ Fourier-transform near-infrared spectroscopy was applied for the reliable determination of monomer conversions and it indicated living characteristics. Both polymerization processes showed an induction period that seems to …
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Síntesis y caracterización de hidrogeles de alginato y n-isopropilacrilamida para aplicaciones biomédicas
… resultó mejor aquella basada en la obtención de PNIPAAm amino terminado (PNIPAAm-NH2), y su posterior injerto en la cadena de alginato mediante la reacción de condensación entre los grupos amino del PNIPAAm y los grupos carboxílicos del alginato, ya que se obtuvieron copolímeros con estructura …
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Self-assembling biomimetic hydrogels with bioadhesive properties for tissue engineering applications
… Thermosensitive poly(N-isopropylacrylamide) (PNIPAAm) was grafted with chondroitin sulfate (CS) (PNIPAAm-g-CS) and blended with aldehyde-modified CS to achieve covalent adhesion upon contact with tissue. Extracellular matrix (ECM) loaded lipid vesicles (liposomes) were incorporated into the …
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Synthesis of reponsive homo- and block copolymers - application to the generation of inorganic-organic nanohybrids
… The synthesis of poly(N-isopropylacrylamide) (PNIPAAm) was investigated by ATRP for subsequent polymer-protein nanohybrid generation. This temperature-responsive polymer was polymerized directly in pure water at a low temperature (4 ºC) by using a functional ATRP initiator which allows …
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Microengineered responsive platforms for spatial and geometrical control of multicellular organizations
… fabricated from poly(Nisopropylacrylamide) (PNIPAAm) responded to temperature by changing their shapes. Spherical microtissues of a single cell type were formed in responsive microwells and recovered by using shape changing properties of microwells. Elastomeric microgrooves were conformally …
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Self-assembled bionanoparticle polymer conjugates for building soft composite membranes
… polymers as Poly(N-isopropylacrylamide)(PNIPAAm) to it using the grafting from approach. PNIPAAm is a well known thermo-responsive polymer exhibiting a LCST of 32±C. After developing the well controlled atom transfer radical polymerization (ATRP) of NIPAAm in water at low temperature, the …
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Development of an Encapsulation Strategy for an Implantable Optical Glucose Sensing Technology Compatible with a Self-Cleaning Membrane
… membrane based on poly(N-isopropylacrylamide) (PNIPAAm) has been proposed. Further, a continuous glucose monitoring system based on a competitive binding assay using Concanavalin A (ConA) as a component in a Förster resonance energy transfer (FRET) approach is being developed for encapsulation …
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Smart magnetic affinity adsorbents
… spacing between the graft sites of polymers), pNIPAAm content, type of affinity ligand and type of protein employed. From the above materials those with polymer chains of sufficient pNIPAAm length and at such spacing allowing their ‘free’ expansion/collapse upon temperature change (especially …
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Nanoscale Hydrogel Films and Polymer Brushes Grafted Onto Nanocapillary Array Membranes for Externally Controllable Size -Selective Molecular Transport
… rates on NCAMs. Molecular transport through the PNIPAAm polymer brush-modified NCAMs was investigated by real-time fluorescence measurements using fluorescein isothiocyanate (FITC) labeled dextrans.
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Bioadhesion to model thermally responsive surfaces
… (mixed SAM) and poly(N-isopropylacrylamide) (PNIPAAm). The synthesis of hexa(ethylene gylcol) alkyl thiol (C11EG6OH) is presented along with the mass spectrometry and nuclear magnetic resonance results. The mixed SAM surface was confirmed to be thermally responsive by contact angle goniometry, …
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Metal-polymer nanoparticulate systems for externally-controlled delivery
… including poly(N-isopropyl acrylamide) (PNIPAAm) and poly(N-isopropryl acrylamide-co-acrylic acid) (P(NIPAAm-co-AA)) nanoparticles were synthesized for these nanocomposites using an aqueous dispersion polymerization method. In addition, nanoparticles of interpenetrating polymer networks …
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A study of inter- and intramolecular interactions through neutron compton scattering and low temperature matrix isolation infrared spectroscopy
… in a solution of poly-N-isopropyl acrylamide (pNIPAAm) passing through a temperature-induced phase change, deuterated polymer/ solvent mixtures were studied on the VESUVIO instrument at the ISIS RAL facility, and the analysis of that data is presented. pNIPAAm and related compounds display a …
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The preparation and characterization of thermo-sensitive colored hydrogel film and surfactant-free porous polystyrene three-dimensional network.
… thermo-sensitive poly(N-isopropylacrylamide) (PNIPAAm) hydrogel film was prepared by firstly synthesizing polymer latex and secondarily crosslinking the nanoparticles and casting the polymers onto glass. The shape-memory effect has been observed when changing the environmental temperature. The …
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Synthese und Charakterisierung dünner Hydrogelschichten mit modulierbaren Eigenschaften
… wurde das temperatursensitive P(n-BuAc)-block-P(PNIPAAm-co-DMIAAm) erhalten, des Weiteren gelang die Darstellung der multi-sensitiven Blockcopolymere P2VP-block-P(NIPAAm-co-DMIAAm) und P4VP-block-P(NIPAAm-co-DMIAAm). Die Blockcopolymere wurden mit variierenden Blocklängen und Verhältnissen sowie …
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Self assembled transmembrane protein polymer conjugates for the generation of nano thin membranes and micro compartments
… thermo responsive poly(N isopropylacrylamide) (PNIPAAm) and the pH and thermo responsive polymer poly((2-dimethylamino)ethyl methacrylate) (PDMAEMA) were conjugated to FhuA and the genetic variants via controlled radical polymerization (CRP) using grafting from technique. These polymers were …
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Ion binding to polymers and lipid membranes in aqueous solutions : Ionenbindung an Polymeren und Lipidmembranen in wässrigen Lösungen
… KCl and NaCl, mit einem neutralen Polymergel, PNIPAAM, und dem geladenen Polymer PAA untersucht. Mit Hilfe von Kalorimetrie und einer kaliumselektiven Elektrode wurde beobachtet, dass die Ionen mit beiden Polymeren wechselwirken, unabhängig davon, ob diese Ladungen tragen, oder nicht.
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Towards greener stationary phases : thermoresponsive and carbonaceous chromatographic supports
… a polymer is the poly (N-isopropylacrylamide) PNIPAAM, where it is dissolved well in water below 32 oC, while by increasing the temperature further leads to its precipitation. In this work, an alternative polymer poly (2-(2-methoxy ethoxy)ethyl methacrylate-co- oligo(ethylene glycol) …
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