Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"PNAG"”.
-
The Development of Substrates and Inhibitors of the PNAG Biosynthetic Machinery
… polymer of β-(1,6)-linked N-acetylglucosamine (PNAG). The protein components that are responsible for the synthesis, modification and export of the PNAG polymer are encoded by the ica and pga operons in S. epidermidis and E. coli respectively. It has been shown that deletions of any of the gene …
-
Modification and Translocation of the Biofilm Exopolysaccharide Poly-β(1,6)-N-acetyl-D-glucosamine
… is poly-beta(1,6)-N-acetyl-D-glucosamine (PNAG). The modification of PNAG through deacetylation and/or hydrolysis by PgaB, BpsB, and IcaB is required for biofilm formation by Escherichia coli, Bordetella bronchiseptica, and Staphylococcus epidermidis, respectively. E. coli PgaB is a …
-
Development of Mono-de-N-acetylated β-(1→6)-N-acetyl-D-glucosamine Substrates for Characterization of PgaB Hydrolase Activity
… poly-β-(1→6)-N-acetyl-D-glucosamine (dPNAG) exopolysaccharide is required for biofilm formation in many clinically relevant bacteria. The PgaABCD biosynthetic machinery is responsible for the synthesis and export of dPNAG in Gram-negative bacteria. PgaB is a two-domain periplasmic …
-
THE SUBTLE BIOFILM REGULATION IN ESCHERICHIA COLI: CSGD AND THE YDDV-DOS OPERON
… fibers, cellulose and poly-N-acetylglucosamine (PNAG), the most important biofilm determinants in E. coli. E. coli is an Enterobacterium, normally living inside the mammalian gut, at temperature of 37° C and in relatively nutrient-rich environment. Once outside the host, bacteria usually face …
-
Biofilm-related Materials as Total N-nitrosamine (TONO) Precursors and Hydroxylamine-based Interferences in TONO and N-nitrosodimethylamine (NDMA) Measurements
… materials - poly-N-acetylglucosamine (PNAG), Pseudomonas aeruginosa, and tryptophan - were individually chloraminated and dose-response relationships were observed with the SPE-TONO assay, indicating biofilm are potential N-nitrosamine precursors. The role of hydroxylamine - a …