Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"PMNs"”.
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Corneal Wound Healing: Cells and Molecules
… of anti-Ly6G antibody to deplete circulating PMNs while others received topical applications of recombinant interleukin-20 (rIL-20) to blunt inflammation. To determine if platelet extravasation was dependent on CD18 expression levels, two groups of mutant mice were studied, one with …
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An audit of the thyroid screening programme in the Peninsula Maternal and Neonatal Services
… in the Peninsula Maternal and Neonatal Services (PMNS) in the 5 year period from 01/01/2000 to 31/12/2004, focusing on coverage, recall rate and success, number of cases detected, incidence of congenital hypothryoidism in this population; and cost efficiency of the programme. All babies born in …
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Untersuchungen zur Rolle von organischen Stäuben in der Pathogenese der exogen-allergischen Alveolitis
… verstärkte chemotaktische Aktivität gegenüber PMNs im Vergleich zur Lavageflüssigkeit von gesunden Kontrollpersonen. Nach Neutralisation von IL-8 durch Zugabe von Anti- IL-8-Antikörpern konnte ein signifikanter Rückgang der Chemoattraktion von PMNs durch die Lavageflüssigkeit festgestellt …
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Circadian Flux of Extravascular Polymorphonuclear Leukocytes in the Mouse Limbus
… cornea, a recent study suggests extravascular PMNs are found at the limbus and their numbers rise and fall in a circadian rhythm, peaking in the evening. Additional studies in other tissues suggest metabolic syndrome resulting from the consumption of a HFD is associated with circadian …
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Role of polymorphonuclear leukocytes in the tumoricidal activity of Propionibacterium acnes
… large numbers of polymorphonuclear leukocytes (PMNs) at 12 hours. To determine the role of PMNs in the killing of tumor cells, tumor cells were incubated with supernatant obtained from the phagocytosis mixture of PHNs and P. genes. After a 2- hr. incubation, the tumor cells were washed and …
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Expression of leukocyte-endothelial adhesion molecules during acute inflammation in the lung
… adhesion is a critical step in the response of PMNsto inflammation. In the systemic circulation, the leukocyte adhesion molecule, L-selectin, facilitates PMN adhesion to inflamed endothelium while CD11/CD18 is required for PMN emigration into extravascular tissues. An inducible endothelial …
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Developing High Purity Embryonic Stem Cell-Derived V2a Interneurons for In Vitro Investigation and Transplantation Following Spinal Cord Injury
… with ESC-derived progenitor motor neurons (ESC-pMNs). Although ESC-V2as did not variably respond to the growth factors applied when cultured in isolation, co-culture with ESC-pMNs improved ESC-V2a neurite extension, survival, maturation, and electrophysiological activity. Application of …
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Staphylococcus aureus Panton-Valentine leukocidin (PVL) alters human neutrophil viability and function
… cells, including polymorphonuclear leukocytes (PMNs or neutrophils). It is widely assumed that PVL-mediated pore formation in the plasma membrane of PMNs leads ultimately to cytolysis. However, this hypothesis has not been tested and previous studies indicate that levels of PVL <i>in vivo</i> …
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Staphylococcus aureus Panton-Valentine leukocidin (PVL) alters human neutrophil viability and function
… cells, including polymorphonuclear leukocytes (PMNs or neutrophils). It is widely assumed that PVL-mediated pore formation in the plasma membrane of PMNs leads ultimately to cytolysis. However, this hypothesis has not been tested and previous studies indicate that levels of PVL <i>in vivo</i> …
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Investigation of the immunological differences between granulocytes from healthy donors and breast cancer patients, with respect to the cancer testis antigen, CTCFL
Granulocytes or Polymorphonuclear neutrophils (PMNs) are key players in the non-specific immune system against microbial infection as they express surface receptors for the recognition of general antigenic patterns found on pathogens. In addition PMN’s also act as a mediator for the …
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Leukocyte Chemotaxis Activity by Cotyledons of Dairy Cows With Normal Delivery and Retained Placenta
… results suggest the following conclusions: (a) PMNs from normally calving cows with retained placenta apparently have a defective chemotaxis when compared with that of PMNs from non-retained placenta cows; (b) in normally calving cows, the number of carnucular cells is significantly lower in …
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Apoptosis of Peripheral Blood Leukocytes in Systemic Lupus Erythematosus: Studies on Serum Induction and Complement-Dependent Clearance Mechanisms
… by polymorphonuclear neutrophil granulocytes (PMNs). Phagocytosis of necrotic material by PMNs and high concentration of antibodies against a broad spectrum of histones correlated with active SLE disease. The specificities of these anti-histone antibodies appear to determine the …
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The Effect of Candida Hyphal Inhibitory Product (Chip) on Murine Peritoneal Macrophage Killing of Candida Albicans Hyphae
… (CHIP) which decreases the efficiency by which PMNs phagocytize C. albicans yeast. The focus of this study was to determine the effect of candida hyphal inhibitory product (CHIP) upon contact-mediated killing of the hyphal form of C. albicans by Listeria monocytogenes activated macrophages. …
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Equine innate and adaptive immunity to viral infections
… expression of equine TLR9 in neutrophils (PMNs), CD4[superscript]+ and CD8[superscript]+ T cells and other leukocytes. Conservation of equine TLR9 and a high expression profile among leukocytes suggests that equine TLR9 is a frequent target for unmethylated CpG-DNA, an essential mechanism …
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Adrenergic Receptor Gene Expression in Bovine Leukocytes and Effects of Adrenergic Agonists on Neutrophil and Eosinophil Function
… cells (PBMCs), polymorphonuclear cells (PMNs), and purified T cells, B cells, monocytes, innate lymphoid cells, neutrophils and eosinophils. While transcript abundance for the β2-, α2A-, and α1A-AR genes tended to be greatest in leukocytes isolated from bovine whole blood, marked …
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The Role of Complement in Ischemic Heart Disease in Type 2 Diabetes Mellitus
… chemoattractant for circulating neutrophils (PMNs). The purpose of this dissertation research was to test the hypothesis that the complement system, predominantly the lectin pathway, is a significant contributor to the excessive response of the Zucker Diabetic Fatty (ZDF), a rat model of T2DM, …
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Phenotyping Ethnic Differences in Body Fat Depots
… present data from Pune Maternal Nutrition study (PMNS) cohort; comprising 423 young adults of SA descent in India. Analyses of body fat phenotype in Cau pre-diabetic populations showed higher VAT (mean differences= 0.5 litre, p<0.0001) and liver fat content (mean differences= 0.6%, p<0.0001), but …
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A Study of Muon Neutrino Disappearance in the MINOS Detectors and the NuMI Beam
… involves two representations related by the PMNS matrix characterized by either distinct mass or flavor. The parameters of this mixing matrix, three angles and a phase, as well as the mass differences between the three mass eigenstates must be determined experimentally. The Main Injector …
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Accelerating NOvA's Feldman-Cousins procedure using high performance computing platforms
… governing neutrino oscillations within the PMNS oscillation model by comparing model predictions to a small data set of neutrino interactions. To account for non-normality, NOvA uses the computationally intensive Feldman-Cousins (FC) procedure, which involves fitting thousands of independent …
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BIOLOGICAL AND TRANSDUCTIONAL EFFECTS OF ALLOSTERIC ANTAGONISTS ON THE ACTIVITY OF CHEMOATTRACTANT RECEPTORS
… blocker of both CXCR1 and CXCR2 expressed on PMNs, lymphocytes, and cells transfectants with a IC50 in the range of 1 to 2 nM. Despite its potency on both CXCL8 receptors, the effect of DF 2156A was highly specific. DF 2156A did not affect the activity of several related chemokine receptor …
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