Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"PLG"”.
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Investigation of protein destabilization in monodisperse poly(lactide-co-glycolide) microparticles
Poly(lactide-co-glycolide) (PLG) microspheres are a powerful choice for controlled release of protein therapeutics. However, several properties of PLG microspheres, particularly hydrophobicity and acidic microenvironment, may have detrimental effects on encapsulated protein, causing structural …
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The Design, Development and Evaluation of a Web-based Tool for Helping Veterinary Students Learn How to Classify Clinical Laboratory Data
… based tool known as the Problem List Generator (PLG) was designed based on current literature dealing with learning theory and medical education which are reviewed in chapter 1. Chapter 2 describes the design and the development process for the PLG. The PLG allows the students to access any …
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Modification of a DNA Vaccine for Oral Administration in Fish for Aquaculture by Using Non-Microbial Nanoparticles
… with chitosan or polylactide-co-glycolide (PLG). The immune response of hybrid striped bass (Morone saxatilis x Morone chrysops) following oral delivery of a DNA vaccine containing Mycobacterium marinum Ag85A plasmid in either chitosan or PLG nanoparticle encapsulation was evaluated. Hybrid …
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Uniform biodegradable microparticle systems for protein delivery
… invasive manner. Poly(lactide-co-glycolide) (PLG) and poly(lactic acid) (PLA) microparticles such as double-wall/monolithic microspheres and microcapsules have been heavily investigated for controlled delivery of small-molecule drugs as well as peptides, proteins and DNA. The size distribution …
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Uniform double wall microspheres/microcapsules for protein delivery
… invasive manner. Poly (lactide-co-glycolide) (PLG) and poly (lactic acid) (PLA) microparticles such as double-wall/single-wall microspheres and microcapsules were heavily investigated for controlled delivery of small molecule drugs as well as proteins and DNA. The size distribution of …
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Purification, immunogenicity and protective potency of the F1 antigen from <i>Yersinia pestis</i>
… delivery systems in poly(lactideco-glycolide) PLG micro spheres and liposomes. Recombinant V was used in addition to F1 to assess a combination subunit vaccine with F1 given alone as an acellular vaccine. <br></br><br></br>F1 antigen encapsulated in PLG microspheres induced high serum antibody …
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Development of P(TMC)-Based Polymers for Sustained Delivery of Acid-Sensitive Drugs
… a polymer called poly(lactide-co-glycolide), or PLG. However, PLG breaks down to form highly acidic by-products, which react with the peptide and alter the drug’s chemistry. Depending on the peptide, this can lead to reduced effectiveness or inactivation. In this work, a P(TMC)-based polymer was …
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Formulation and characterisation of cationic microparticles for the delivery of DNA vaccines
… the surface of poly (D,L-lactide-co-glycolide) (PLG) microparticles stabilised with the surfactant cetyltrimethyl ammonium bromide (CT AB). This work demonstrated the induction of antibody and cellular immune responses to HIV proteins encoded on plasmid DNA adsorbed to the particle surface in …
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Interactions of Francisella Tularensis With Components of the Host Fibrinolytic System
… FT-bound host proteins.</p> <p>Plasminogen (PLG) is a zymogen that upon activation is converted into the serine protease plasmin, which plays a key role in the proteolytic degradation of fibrin blood clots. Many pathogenic organisms have taken advantage of both the broad-specificity and …
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Proteolyse-induzierte Spaltprodukte des Plasminogens
… Kapazität in den Exsudaten und der MPlg-Entstehung ließ sich nicht zweifelsfrei beweisen. MPlg ist daher – im Gegensatz zu dem Elastase-spezifischen Spaltprodukt des Fibrinogens (FEP) (Gippner-Steppert, 1991) - als ein spezifisches Spaltprodukt des Plg nicht für den indirekten …
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Teaching and learning pedagogies to enhance practice in Higher Education: a practitioner’s perspective
… the students, working in peer learning groups (PLGs), connecting with each other very early on in their programme and sharing metaphors was found to have value. Learning in a university has been shown to be an isolating experience and working together has merits for both staff and students. This …
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Redefining luxe boundaries - Luxury goods value perceptions and consumer purchase behaviours from the lens of Cadillac in UAE
… thematic corollary between Cadillac and PLG in the UAE. The findings hope to inspire other academics and practitioners to examine similar affinities, beyond just auto-personal luxury combi but other permutable combinations; as well as encouraging future research focus on the Middle East …
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THE OMEGA-6: OMEGA-3 FATTY ACID RATIO IN SWINE NUTRITION: LONG-TERM EFFECTS ON PERFORMANCE, MILK FATTY ACID PROFILES, OXIDATIVE STATUS, AND PROTEOMES
… proteins (F2, HRG, ORM1); coagulation regulator (PLG); and APPs (HP, ITIH4, TF, SAA, SERPINA1). These proteins participate in platelet metabolism, haemostasis, and cross-talk between coagulation pathways and inflammation, particularly in the innate immune system. Piglet ileum proteomics: Maternal …