Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 65 for “"PKS"”.
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Implementasi kafa'ah dalam perspektif Partai Keadilan Sejahtera (PKS): Studi pandangan elit Partai Keadilan Sejahtera di DPW PKS Sulawesi Selatan
… bahwa para elit Partai Keadilan Sejahtera (PKS) Sulawesi Selatan memberikan perhatian secara penuh terhadap kader-kader mereka dalam memilih jodoh dengan sesama kader partai mereka. Terkait perkawinan di kalangan kader PKS di Sulawesi selatan yang memiliki kecenderungan menikah sesama kader. …
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The optical polarization variability of the blazar PKS 2155 304
… by the magnetic field of a relativistic jet. PKS 2155–304 is an archetypal blazar, located in the southern hemisphere. The source is bright and highly variable, displaying both active and quiescent states. In this thesis I make use of optical polarization and multiwavelength observations …
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Physics from Time Variability of the VHE Blazar PKS 2155-304
… gamma-ray telescopes such as H.E.S.S., and PKS 2155-304 is the prototypical southern-hemisphere representative of this population of objects. In this thesis I have studied in detail some aspects of the temporal variability of the jet emission from PKS 2155-304, combining coordinated …
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Investigation of artificial malonyl group carriers and multifunctional cyclic scaffolds towards the mimicry of PKS
… in order to mimic part of the active site of a PKS. The new mercapto-calix[4]arene prepared, which carries two sulfhydryl groups in the upper rim, has been successfully loaded with two malonyl molecules and employed to mimic the condensing function of PKS.
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Very high energy emission and multi-wavelength campaigns of the BL Lac object PKS 2155-304.
… hemisphere high energy BL Lac object, (HBL), PKS 2155-304. After a general introduction covering the particulars of Active Galactic Nuclei, the pysical processes and models that are believed to play an important role in the observations and ground based γ-ray astronomy, the results and …
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Inserting non-muslims into the Islamic party : the Prosperous Justice Party (PKS) between political pragmatism and ideological coherence
… influencing the Prosperous Justice Party (PKS) in Indonesia to include non-Muslims as members and candidates, examining the balance between political pragmatism and ideological coherence. The central argument posits that PKS’s insertion of non-Muslims is a strategic adaptation to …
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Characterization of chalcone synthase genes in red raspberry cultivar (rubus idaeus)
… involves type III polyketide synthases (PKSs): chalcone synthase (CHS), which is the first enzyme of the flavonoid synthetic pathways leading to synthesis of various anthocyanins. The European red raspberries are a commercially important fruit that needed both for fresh fruit consuming …
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Studies Towards the Discovery of Novel Natural Products Through Functional Analysis of Environmental DNA-Encoded Type II Polyketide Synthases
… synthesized by Type II polyketide synthases (PKSs) in soil-borne bacteria. Through the functional characterization of soil eDNA-derived Type II PKS containing clones, herein we attempt to identify novel PKS systems that encode structurally diverse metabolites and explore their biological …
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Novel Molecules from Environmental DNA-Derived Type II Polyketide Biosynthetic Gene Clusters
… found to be rich in type II polyketide synthase (PKS) gene clusters (Kieser, Bibb et al. 2000). PKS gene clusters produce a structurally diverse collection of aromatic natural products. The nascent polyketide in these pathways is produced by a conserved minimal PKS, composed of an α- ketosynthase, …
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Entwicklung der Spiegelmechanik, Eichung der Kamera und erste Ergebnisse zum Nachweis hochenergetischer gamma-Strahlung aus Richtung des Krebsnebels und PKS 2155-304 mit dem ersten H.E.S.S.-Teleskop
… erster Beobachtungen des Krebsnebels und von PKS 2155-304. Zur Analyse wurden 2 verschiedene Simulationen (S1, S2) verwendet. Das differentielle Energiespektrum des Krebsnebels zwischen 0,57 und 5 TeV wurde mittels der effektiven Flächen von S1 zu (3,04 +/- 0,57(stat)) * 10^(-7) * E^(-2,49 +/- …
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Biosynthetic characterisation of secondary metabolites from stromatolite cyanobacteria Symploca sp. 1013
… due to the presence of polyketide synthase (PKS) or non-ribosomal peptide synthetise (NRPS). Bioactivities in areas such as antibacterial, antifungal and anticancer have been implicated in many of these metabolites. In the present study, various marine cyanobacterial isolates from from …
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Fatty acid metabolism of marine microalgae
… which was shown to employ a polyketide synthase (PKS) complex for primary DHA biosynthesis. Additionally, genes of the Schizochytrium PUFA-PKS were successfully expressed in transgenic yeast, which produced DHA. Candidates for genes encoding C. cohnii PUFA-PKS components and other genes of C. …
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Functional Analysis of Secondary Metabolite Biosynthesis-Related Genes in Alternaria brassicicola
… synthetases (NPSs) and 10 polyketide synthases (PKSs) in the A. brassicicola genome. The phenotype resulting from knockout mutations of each PKS and NPS gene was investigated with an emphasis on discovery of fungal virulence factors. A highly efficient gene disruption method using a short linear …
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Mass Spectrometric Studies of Nonribosomal, Enzymatic Assembly of Natural Products Through Thiotemplate Biosynthesis
… in-depth application of FTMS to the study of NRP/PKS enzymes for the elucidation of natural product biosynthesis. The reliance of FTMS will continue to improve and should prove itself worthy of the best analytical assay tool for uncovering the intricate mechanisms of thiotemplate enzymes.
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Studies of new natural products and their biosynthesis spearheaded by high-resolution mass spectrometry
… synthetases (NRPSs) and polyketide synthases (PKSs). In NRPS and PKS biosynthesis, monomer units are incorporated into a growing natural product chain in an assembly line fashion using a covalent thiotemplate mechanism. Because the growing natural product is covalently tethered to the enzyme, …
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Entdeckung des neuen Candidatus Phylums Poribacteria
… APAE02 neuartige Typ I Polyketidsynthasen (PKS) nachgewiesen werden. Phylogenetische Analysen der Ketosynthasedomäne zeigten, dass diese Systeme nicht herkömmlichen Typ I cis-AT bzw. trans-AT (Acyltransferase) PKS Systemen zugeordnet werden können. Die kodierenden Bereiche der PKS Systeme …
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Analysis of the diverse antibacterial strategies used by <i>Serratia marcescens</i> Db10
… synthetases (NRPS) and polyketide synthases (PKS) are widespread in bacteria and fungi and are responsible for the biosynthesis of many metabolites with medically relevant properties, including antibiotics. The activity of NRPS and PKS enzymes is dependent on their modification by a …
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Discovering novel natural products from bioactive plants and bacteria
… strategy for cloning and characterizing Type III PKS genes that are likely responsible for the synthesis of novel natural products from Eucalyptus species. Nested degenerate primers were designed and a total of 94 clones and 27 clones were sequenced from the cDNA libraries created from the leaves …
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Cyclization modes in type III polyketide synthases and the synthetic compounds used as probes for mechanistic studies.
Type III polyketide synthases (PKS) catalyze different cyclization reactions of linear polyketide intermediates to produce polyketides with distinct ring structures. The mechanisms of pyrone and resorcinol ring formation in type III PKSs remain unknown, despite many years of research on this family …
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Analysis and Engineering of Polyene Biosynthesis in Actinomycetes
… evolution" was explored with the clethramycin PKS, which had previously been used to generate multiple analogues of the polyketide rapamycin. In this approach, recombination within the homologous modules of a PKS is stimulated and the resulting progeny are examined for the production of novel …
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