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Showing 1 to 20 of 34 for “"PHAGOCYTIC ACTIVITY"”.
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ΡΙΤΟΔΡΙΝΗ ΚΑΙ ΕΝΔΟΚΥΤΤΩΣΗ (ΠΕΙΡΑΜΑΤΙΚΗ ΕΡΓΑΣΙΑ IN VIVO)
THE EFFECT OF RITODRINE ON THE PHAGOCYTIC ACTIVITY OF THE MONONUCLEAR PHAGOCYTES (M.P.S.) WAS STUDIED IN VIVO. THE CLEARANCE OF A CERTAIN QUANTITY OF CARBONPARTICLES (250A) FROM THE CIRCULATION WAS TAKEN AS AN INDICATOR OF THE PHAGOCYTIC ACTIVITY OF MPS ACCORDING TO THE METHOD PROPOSED BY HALPERN …
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Identification of Functional Immunological Indicators of Nutritional status during acute nutritional deprivation
… its components. The sensitivity of monocyte phagocytic activity, major histocompatibility complex (MHC) class II expression, and fibronectin concentration were studied in 23 healthy cats during a 7 day period without food followed by a 7 day refeeding period. Blood samples were obtained for …
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LPS, A TLR-4 AGONIST AND VIPER A TLR-4 INHIBITOR UPREGULATE PHAGOCYTOSIS OF ZYMOSAN IN BV2 CELLS
… homeostasis by having an active but yet balanced phagocytic activity. However, in various CNS related diseases, microglia cells have been shown to malfunction. In Alzheimer's Disease (AD), hyperactive microglia with impaired phagocytic activity is the main hallmark of this disease, along with the …
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Understanding the Effect of BVDV on Innate Immune Response of Neutrophils
… significantly enhanced neutrophil phagocytosis activity for 0.2 μm microsphere beads as compared to mock infection. Neutrophil phagocytic activity for rhodamine-labeled E. coli was reduced by BVDV infection as compared to LPS-control. TGAC, TGAN, 1373 or 28508 had 23%, 6%, 19% or 12% less …
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Copper supplementation and monocyte function in growing beef calves
… in both a greater number of cells exhibiting phagocytic activity, as well as, an increased phagocytic capacity compared to monocytes recovered by the IM technique. Culture flask adherence appears to be an efficient technique for isolation of a viable, homogeneous population of bovine …
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Human Chimeric Antigen Receptor Macrophages For Cancer Immunotherapy
… tumor-associated antigens could redirect their phagocytic activity and lead to therapeutic efficacy with the potential for the induction of an anti-tumor T cell response. In this thesis, we demonstrate that CD3-zeta based CARs are capable of inducing phagocytosis by human macrophages. Notably, …
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Macrophage Suppression Across Genetic Barriers By a Spleen Cell Culture Derived Factor
… and an assay for the maintenance of biological activity across genetic barriers. Suppression of phagocytic activity of C57BL/10J PEC by MSF derived from BALB/c mice and likewise, activity of BALB/c PEC with MSF from C57BL/10J mice was compared to controls. The degree of suppression by …
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Characterization of a Nanoparticle Drug Delivery System for the Treatment of Inflammation in Spinal Cord Injury
… microglia/macrophage as part of their endocytic/phagocytic activity in removing foreign bodies. Microglia assume phagocytic activity after traumatic stimuli and this makes NPs an excellent tool for carrying drug to these cells. So, in order to counteract this deleterious pro-inflammatory …
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Effects of Spaceflight on Phagocytic Function and Immune-Neural Interaction
… in leukocyte populations, cytokine secretions, phagocytic activity, bacteria clearance, Major histocompatibility complex class II (MHC II) expression and cFos in the paraventriculuar nucleus (PVN) were characterized. We then examined the effects of body-only proton radiation exposure on …
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Novel Characteristics of Murine Bone Marrow-Derived Macrophages and Human Macrophage-Like Cells
… as macrophages based on surface proteins and phagocytic activity but produced only low levels of the cytokines tumor necrosis factor-α and interleukin-lβ. Cytokine production did not increase in response to the bacterial endotoxin lipopolysaccharide (LPS). Generation of these macrophage-like …
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Splenic Regulation Of Cell Mediated Immunity To Listeria Monocytogenes: Suppression Of Macrophages
… that splenectomized mice have increased phagocytic activity. The nature of splenic regulation of macrophage activity was investigated. To determine if suppression was cellular or humoral, splenectomized mice were reconstituted with normal syngeneic spleen cells and normal plasma from …
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Studies on the Cellular Responses and Roles of Microglia, Astrocytes, and Blood-Derived Inflammatory cells in Injured Rat Brain
… Monocytes rather expressed CD68, a marker of phagocytic activity. Importantly, the total number of dopaminergic neurons in the SNpc at 3 h (~80% of that in the contralateral side) did not decrease further at 7 d. Similarly, in the cortex, ATP-induced neuron-damage area detected at 3 h did not …
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Dosage Window of Selenium on Human Natural Killer Cytotoxicity and Neutrophilmediated Chemiluminescence
… induced both enhancement and depression of activity. The existence of a narrow dosage-window is evident.</p> <p>The activity of the selenoenzyme glutathione peroxidase (GSH-Px) was also determined in NK cells and phagocytes following selenite supplementation. Dose-dependent augmentation of …
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Immune Function Determination in Mice Dermally Exposed to Permethrin
… termination of exposure, but macrophage phagocytic activity was not affected. Cell surface markers of thymocytes, splenocytes and bone marrow cells were not affected. Antibody production as shown by plaque forming cell (PFC) assay decreased significantly at 10 days after dosing …
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Role of the Nfa1 Protein in Pathogenic Naegleria fowleri Co-cultured with Target Cells
… on pseudopodia and in a food-cup formed as a phagocytic structure close contact with target cells. The amount of nfa1 mRNA of N. fowleri was strongly increased at 6 hr post co-culture. Finally, it was elucidated that the Nfa1 protein played an important role in phagocytic activity, a …
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Effects of Stress on Several Immune and Health Responses of Weanling Calves
… counts, and glutathione peroxidase (GSH-Px) activity for erythrocytes and leukocytes were measured for each calf at each date. Erythrocyte GSH-Px activity remained constant over time, while leukocyte GSH-Px and serum Se increased on d 7 (P<0.0001). Effects of single mineral vs. multi-mineral …
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Investigating the inhibitory effects of secreted proteins on macrophage in glioblastoma
… to immune suppression and inhibition of T cell activity through secreted immuno-suppressive proteins and cytokines, dysfunction of immune cells and upregulation of immune checkpoint molecules. Macrophages are the most populous non neoplastic cells in glioblastoma microenvironment, which is a …
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Deciphering Underlying Mechanisms Of Photoreceptor Outer Segment Degradation; Involvement Of Intracellular Trafficking
… can become impaired. Impairment in this unique phagocytic process can lead to degeneration of the RPE cells as well as the adjacent photoreceptor cells. In order to understand the pathogenesis of AMD and other retinal degenerative diseases it is important to uncover the molecular factors that …
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Investigation of the immunological differences between granulocytes from healthy donors and breast cancer patients, with respect to the cancer testis antigen, CTCFL
… The first part of our experiments assessed phagocytic activity, oxidative burst function, survival and expression of immunity receptors in BORIS-positive PMN cell-line model. The second part investigated the origin of CTCFL activation by the incubation of peripheral human PMN’s with the …
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