Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"PGE1"”.
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Binding and Signaling Differences between Prostaglandin E1 and E2 Mediated by Prostaglandin E Subtype Receptors
Prostaglandin E1 (PGE1) and E2 (PGE2) are ligands for the prostaglandin E2 receptor (EP) family, which consists of four subtype receptors, designated as EP1, EP2, EP3 and EP4. Interestingly, PGE2 mediates inflammation whereas PGE1 acts as an anti-inflammatory factor. However, the molecular basis of …
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Validación de los procedimientos diagnósticos en la disfunción eréctil
… parámetros analíticos y la inyección de PGE1 con estímulo visual erótico y estímulo visual neutro
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Regulation of IL-6 signal transduction, contributions of the Signal Regulatory Protein (SIRP) and cyclic AMP
… in NHDF cells stimulated with prostaglandin E1 (PGE1), known to activate adenylate cyclase. Furthermore, with the help of specific prostagalndin EP2 receptor agonist (R-butaprost), a receptor mediated PGE1-dependent ERK inhibition was identified. Protein kinase A (PKA) activated by cAMP was shown …
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Synthetic studies on prostaglandins: "synthesis of a new thia-PGEI analog"
A PGE1 analog, namely (±)-trans-2-(6'-carbomethoxyhexyl)-3- (E-3"-thia-1 "-octene)-4-hydroxycyclopentanone 71, has been prepared for the first time. Towards the synthesis of this compound, several synthetic approaches aimed at the preparation of the required acetylenic and E-halovinylic sulfides as …
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An examination of the bioactive lipids involved in skin cell inflammation and in response to ultraviolet radiation. Effect of n-3 polyunsaturated fatty acid supplementation on red blood cell and human dermal fatty acid and production of eicosanoids by HaCaT keratinocytes and 46BR.1N fibroblasts following exposure to UVR.
… cell; respectively). Significant increase in PGE1 and PGE2 occurred when cells were exposed to 15mJ/cm2 UVR. Treatment with n-3 PUFA decreased the level of PGE1 and PGE2, and increase production PGE3 at the baseline and post UVR. Both cell lines produced hydroxy fatty acids and the …
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The influence of the hormonal milieu on eicosanoid and cytokine production in tissues from the female reproductive tract.
… in human myometrium. Production of 6-keto-PGF1¿, PGE1 and PGF1¿ increased whilst 15- keto PGE2 and PGJ2 decreased at term pregnancy (37-41 weeks gestation) versus non-pregnancy (p<0.05). Myometrium from parturient donors synthesised TXB2 and PGE2 more abundantly than the non-labouring equivalent. …
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Role of an Adenylyl Cyclase Isoform in Alcohol's Effect on Cyclic AMP Regulated Gene Expression in Mammalian Cells
… via stimulation with prostaglandin E1 (PGE1) showed an increase in cAMP and reporter gene expression in RAW 264.7 and BV-2 cells. The effect observed was potentiated in the presence of ethanol. Cyclic AMP analog, 8-Bromo-cAMP, induced luciferase activity was not significantly affected by …
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Compuestos bioactivos en vino tinto y su efecto sobre el estrés oxidativo y marcadores vasculares, de inflamación, mutagénesis y degeneración del sistema nervioso central tras su ingestión dietética por voluntarios sanos
… aumentar la de prostaglandinas vasodilatadoras (PGE1), mediada por su contenido en melatonina e hidroxitirosol. La ingesta de vino tinto reduce el estrés oxidativo del sistema nervioso central, medido por la excreción de neuroprostanos y F2-dihomo-isoprostanos en orina, en mayor medida que la …