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Showing 1 to 1 of 1 for “"PGC-1 isoforms"”.
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Investigating the functions of PGC-1 isoforms in retinal pigment epithelia metabolism and their implications on age-related macular degeneration
… damage. The transcriptional co-activators, PGC-1α and PGC-1β, are important regulators of mitochondrial biogenesis and anti-oxidant capacity. Our group has previously shown that the PGC-1α protein promotes RPE oxidative metabolism and that overexpression of the PGC-1α gene protects cells …