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Showing 1 to 20 of 44 for “"PFOA"”.
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Epigenetic toxicity of PFOA in HepG2 cells and its role in lipid metabolism
Perfluorooctanoic acid (PFOA), a man-made stable perfluoroalkyl acid is used widely in the process of synthesizing fluoropolymers for the manufacturing of various daily products such as Teflon. PFOA is extremely persistent in the environment and can be detected in many organisms including humans. …
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Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonate (PFOS) in an Aquatic Ecosystem - Distribution and Fate
Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) belong to the family of perfluorinated surfactants (PFSs). They are widely distributed and persistent in the environment. For over 50 years, they have been used in numerous applications including paper and textile treatment, production …
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Photocatalytic Degradation of Perfluorooctanoic Acid in Water by Free and Immobilised ZnO, g-C3N4 and Their Composite under UV and Visible Light Irradiation
Perfluorooctanoic acid (PFOA) is among perfluoroalkyl and polyfluoroalkyl substances (PFAS) that is widely detected in the environment. ZnO and graphitic carbon nitride are among the most economical semiconductors which have not been widely used for PFOA decomposition. Therefore, ZnO could be an …
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A Review of Perfluorooctanoic Acid Carcinogenicity and Application to Human Risk
Perfluorooctanoic acid (PFOA) is a synthetic organic chemical that consists of an 8 carbon alkyl chain with a terminal carboxyl group in which the carbon-hydrogen bonds have been replaced with carbon-fluorine bonds except at the terminal carboxyl end. This perfluoralkyl carboxylate is a …
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The Biomechanics of Sit-to-Stand and Physical Performance in Patellofemoral Osteoarthritis
… than 55 years of age. Isolated radiographic PFOA is present in 13.6-24% of females and 11-15.4% of males with knee pain. Biomechanical factors such as tibiofemoral alignment and high joint stress are associated with the development and progression of PFOA. PF joint stress is high when the …
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Impacts of perfluorooctanoic acid on porcine oocyte health and competence
… and somatic cells. Perfluorooctanoic acid (PFOA) is a PFAS that is of rising concern to human and animal health which is detected both in Iowa drinking water and human biological samples. PFOA is known to interact with albumin, a protein constituting over 50% of the protein fraction of …
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Accumulation of perfluorooctanoic acid in intestine and lung tissues and its effect on gene expression across multiple pathways
Perfluorooctanoic acid (PFOA) a most common Per- and polyfluoroalkyl substances (PFAS) is a ubiquitous and persistent environmental pollutant. Humans are exposed to it via drinking water, food and airborne dust particulates. Due to its stable nature and slow biological clearance, it remains for …
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Fate and Bioavailability of Per- and Poly-Fluorinated Substances (PFASs) in Soils
… that sorption of 14C-perfluoroocatanioc acid (PFOA) was considerable on common laboratory consumables, e.g. centrifuge tubes and syringe filters. In contrast to reports in the literature, sorption losses on polypropylene tubes were found to be significantly higher than on glass tubes. Sorption …
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Investigating mechanisms of ovotoxicity of Perfluorooctanoic acid and Zearalenone exposure and the influence of altered metabolic status on ovarian function
… to the ovotoxicants perfluorooctanoic acid (PFOA) and zearalenone (ZEN) was investigated. The rationale for this hypothesis was based upon similar metabolic alterations including hyperinsulinemia between obesity and heat stress in females. A study to evaluate obesity-induced alterations to …
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Identification of Metabolic Markers as Potential Early Predictors of PFAS- Induced Immunotoxicity
… legacy long-chain PFAS (perfluorooctanoic acid, PFOA, and perfluorooctanesulfonic acid, PFOS) suppress both the T-cell-dependent (TDAR) and T-cell-independent antibody responses (TIAR). Previous studies have demonstrated that exposure to PFAS is associated not only with suppression of the TDAR …
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Towards understanding the fate of perfluoroalkyl compounds (PFCs) within urban environments: implications for human exposure.
… sulfonate (PFOS) and perfluorooctanoic acid (PFOA) have been detected across the globe in a variety of media. The toxicity of these compounds and other precursors has led to concern about human exposure. The purpose of this thesis is to investigate the presence of perfluoroalkyl compounds …
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Acetylene Functionalized Photocatalytic COFs for PFAS Adsorption and Degradation
… absorb and photodegrade Perfluorooctanoic Acid (PFOA). Photodegradation experiment results indicate that the Porphyrin-COF has the highest efficiency for PFOA adsorption and degradation, with over 80% PFOA adsorbed and degraded within 3 hours of irradiation.
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Transport of Per- and Polyfluoroalkyl Substances (PFAS) at a Managed Aquifer Recharge Site
… acid (PFHpA), and perfluorooctanoic acid (PFOA). Among these PFAS, five are short-chain compounds (PFBA, PFBS, PFPeA, PFHxA, and PFHpA) and two are long-chain compounds (PFHxS and PFOA). The fluorocarbon chain length among these compounds ranges from four (PFBA) to seven (PFOA). Two …
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Metabolic, neurotoxic and immunotoxic effects of PFAAs and their mixtures on the proteome of plasma and head kidney from rainbow trout
… - 500 ng/L) and individual PFAAs (25 nM of PFOS, PFOA, PFBS or PFBA). Untargeted proteomics and phosphorylated metabolomics were conducted on the blood plasma and head kidney tissue to evaluate differences in biological effect for congeners and mixtures. The mixture and PFOS exposures …
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A Computational Approach to Efficient Electrode Material Design for Electrochemical Oxidation of PFAS
… of EAOP, focusing on perfluorooctanoic acid (PFOA) as a model contaminant. Through quantum mechanical simulations, the initial steps of EAOP, mainly the decarboxylation and chain-shortening reactions, are systematically explored. The effects of surface termination, PFOA orientation, explicit …
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Use of Extraction Technologies in Food Safety Studies
… ideal coating materials for non-stick cookware. PFOA is bioaccumulative, persistent, and potentially harmful to humans. PFOA is not supposed to be found in the final products of non-stick cookware after processing. A method for determination of the leaching of PFOA from the cookware under …
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DEVELOPMENT OF NOVEL ADSORBENTS FOR THE REMOVAL OF EMERGING CONTAMINANTS FROM WATER AND WASTEWATER
… of 12), more than 99% of perfluorooctanoic acid (PFOA) (in single component) and more than 90% of most of the PFCs (mixture of 10), and a maximum of 90% removal in case of BPA. The adsorption capacity of the developed adsorbent was observed to be higher for the removal of 17β-estradiol and PFOA …
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An uncertainty-focused approach to modeling the atmospheric chemistry of persistent organic pollutants
… and find that it reproduces Arctic deposition of PFOA effectively. Given the most recent precursor emission inventory, the atmospheric indirect source of PFOA and PFNA is 10-45 t/yr globally and 0.2-0.7 t/yr to the Arctic.
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Navigating the Unregulated: A Multi-Tiered Public Health Risk Assessment of PFAS and N-DBPs Utilizing Unregulated Contaminant Monitoring Rule Data
… long-chain PFAS (e.g., Perfluorooctanoic acid (PFOA), Perfluorooctane sulfonate (PFOS), and Perfluorodecanoic acid (PFDA)) contribute to non-carcinogenic risk, the short-chain Perfluorohexane sulfonic acid (PFHxS) exhibited a Hazard Quotient (HQ) that exceeded the safety threshold by over two …
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Evaluation of PFAS in Environmental Solids: Retention Devices and a Screening Method
… each material across a range of spiked DOC and PFOA concentrations. DOC was found to facilitate fluorine sorption to both materials. SiltSoxx in the presence of high and low DOC had higher partition coefficients than straw wattle. SiltSoxx also had higher average sorbed concentrations than straw …
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