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Showing 1 to 2 of 2 for “"PFKFB2"”.
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Insights into the Development of Chemotherapeutics Targeting PFKFB Enzymes
… citrate inhibition on the heart PFKFB isoenzyme, PFKFB2. High levels of citrate, an intermediate of the TCA cycle, signify an abundance of biosynthetic precursors and that additional glucose need not be degraded for this purpose. Previous studies have noted that citrate acts as an important …