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Showing 1 to 2 of 2 for “"PFF1010c"”.
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Characterization of PFF1010c, a type IV Plasmodium fasciparum heat shock protein 40
… conditions that prevail in the host environment. PFF1010c is a type IV P. falciparum heat shock protein 40. PFF1010c is predicted to be expressed only at the gametocyte stage of the malarial parasite’s life cycle. The aim of the current study was to investigate the expression PFF1010c by parasites …
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Characterization of Plasmodium falciparum PFF1010c and screening of pyrimidine-quinoline hybrids as inhibitors of HsP70-HsP40 functional partnerships of the Malaria parasite
… and stimulates its ATPase activity, while PFF1010c (PF3D7_0620700.1) is a type IV Hsp40 found in the gametocytes that is yet to be characterized. The current study explored pyrimidine-quinoline hybrid (PQH1-4) compounds as possible inhibitors of PfHsp70-1 interaction with PfHsp40. …