Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"PFF"”.
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Developing an a-synuclein in vitro model for therapeutic testing for Parkinson's disease
… imaging study of α-synuclein pre-formed fibril (PFF) seeding, α-synuclein PFF cellular uptake, induced pathology, and characterisation of the model, including morphological and phenotypic changes, as well as investigations into synapse loss and cell toxicity. The study demonstrated that …
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Quantification of membrane transport rates using optofluidics
… with a novel Pinched Flow Fractionation (PFF) purification module. PFF removes formationassociated residues at a range of length-scales, from surfactant molecules to oil droplets, with high efficiency, leading to more homogeneous model systems for transport studies. The application of PFF …
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The Piezoresistive Effect In Microflexures
… (FEA). The piezoresistive FEA for flexures (PFF) algorithm is an FEA implementation of the unidirectional form of the model for flexures. A case study is then given in which the resistance curves of two test devices are predicted with the PFF algorithm. Results from the PFF implementation of …
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The Variability of Strains in Bolts and the Effect on Preload in Jointed Structure
… this research uses the Peak Finding and Fitting (PFF) PFF algorithm to analyze nonlinear dynamics of the experimental system, which demonstrates the ramifications of the experimental results. Measured strains in bolts showed significant variabilities, which indicates larger the expected …
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The microbiome-gut-brain axis in preclinical alpha-synuclein models of Parkinson's disease
… α-synuclein monomers or pre-formed fibrils (PFF) were injected into the duodenal wall. This study revealed that injection of α-synuclein monomer or PFF caused GI dysfunction including decreased faecal output and water content, and enteric neuronal degeneration after one month, which had …
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Is virtue its own reward? : Exploring philanthropic family foundations & the two faces of altruism
… giving within Philanthropic FamilyFoundations (PFFs). These under-researched organisations represent one structured vesselthrough which successful family enterprises can contribute to society beyond the commercialobjectives of wealth creation and economic development. Recognising the …
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Examining the academic experiences of minorities preparing for the professoriate
… in the Preparing Future Faculty program (PFF). As a consequence of participating in the PFF program, the minority participants regarded that they felt ready for a faculty position, regarded that mentoring was effective, indicated that awareness of faculty roles and responsibilities were …
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Flood risk assessment using multi-sensor remote sensing, geographic information system, 2D hydraulic and machine learning based models
… fluvial floods (FF) with pluvial flash flood (PFF) events occur simultaneously. A hydraulic 2D high-resolution sub-grid model of hydrologic engineering centre river analysis system was performed to simulate FF probability and hazard. Moreover, machine learning random forest (RF) method was used …
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Modulation of DNA repair pathway after CRISPR/Cas9 mediated Double Stranded Break
… were transfected into porcine fetal fibroblast (PFF) cells and the cells were treated with various chemicals that were known to inhibit NHEJ or stimulate HR. Among the chemical treated groups, cells treated with thymidine showed an average of 5.85-fold increase in HDR compared to the control …
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Clinical Applications of Neuromonitoring Following Acute Brain Injury
… forward (CFF) and pulsatile blood flow forward (PFF) models can approximate CaBV with derived TCD signals; CFF best models TCD pulsatility. VI. The pressure reactivity index (PRx) and the pulse amplitude index (PAx) can be estimated non-invasively using slow waves of TCD estimated by CaBV with …
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Factors influencing in vitro maturation of pig oocytes
… after in vitro fertilization. Addition of 10% pFF in combination with gonadotropins during maturation provided the best environment for in vitro maturation with the highest percentage of oocytes reaching nuclear and cytoplasmic maturation. Addition of various levels of estrogen, progesterone …
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Investigations on the structure-toxicity relationship of different alpha-synuclein aggregates associated with Parkinson's disease
… PD model, referred to as the preformed fibrils (PFF) PD mouse model, has been shown to reproduce many features of PD, although a great variability of phenotypes has been reported. Here, we studied how the preparation and storage of different alpha-synuclein conformers can influence this model. We …
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Pulsed Laser Dielectric Ablation for Copper-plated Silicon Solar Cells
… achieved without significantly reduced VOC and pFF. It is shown that the use of pulsed LIP of Ni can be used to improve the busbar adhesion through enabling a greater density of Ni nucleates which can act as adhesive anchor points along busbars. However, the improvements in adhesion may not be …
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Aplikace metody diskontovaného peněžního toku při hodnocení investičního projektu malého ruského podniku
The aim of the thesis is the determination of investment cash flows generated from Finnish market development activities of a selected Russia-based small company, performing investment valuation using discounted cash flow method and presenting improvements which can rise the attractiveness for …