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Showing 1 to 2 of 2 for “"PEX2"”.
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The Mechanism of Mammalian Pexophagy
… characterize the peroxisomal E3 ubiquitin ligase PEX2 as the causative agent for mammalian pexophagy, identify two peroxisomal membrane proteins which are ubiquitinated by PEX2, and identify NBR1 as the primary receptor in PEX2-mediated pexophagy. In the fourth chapter, I examine the regulation of …
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Investigation of pexophagy and autophagy occurrence in Arabidopsis
… of autophagy (atg mutants), I found that pex2, pex4, pex10, and pex14 mutants stabilized several peroxisomal proteins similarly to atg mutants in darkness conditions. I also examined autophagy and pexophagy induction using immunoblotting to detect cleavage of autophagy and pexophagy …