Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"PET/MR"”.
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Improved quantification in small animal PET/MR
… The combination of magnetic resonance imaging (MRI) and positron emission tomography (PET) provides excellent soft tissue contrast from MRI with exceptional sensitivity and specificity from PET. This thesis explores the use of sequentially acquired PET and MR images to improve the quantification …
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PET-MR Imaging of Hypoxia and Vascularity in Breast Cancer
… ultrasound (US) and magnetic resonance imaging (MRI) play an important role in the diagnosis and management of breast cancer; they are generally utilised to provide anatomical or structural description of tumours in the clinical setting. It is widely accepted that the tumour microenvironment …
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The assessment of biomechanical modelling and PET/MR imaging in coronary atherosclerosis
… angiography (CTA), magnetic resonance imaging (MRI) and positron emission tomography (PET) have been developed to characterise lesion morphology, composition, function and metabolism. However, the overall predictive power of an imaging-defined high risk feature for future ischaemic events is …
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Novel applications of fluorine-18 labelled radiotracers in cardiovascular disease
… amalgamation of positron emission tomography (PET) with computed tomography (CT) and magnetic resonance (MR) imaging has allowed for the identification of physiological abnormalities which, in addition to established anatomical features, permit more accurate identification of high-risk coronary …
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Improving Attenuation Correction In Hybrid Positron Emission to mography
… emission tomography imaging techniques such as PET/CT and PET/MR have undergone significant developments over the last two decades and have played increasingly more important roles both in research and in the clinic. A unique advantage PET has over other clinical imaging modalities is its …
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Optimisation of molecular imaging using 11C-methionine PET in the detection of pituitary adenomas
… parasellar region. Magnetic resonance imaging (MRI) is the investigation of choice, and for the majority of patients combined T1 and T2 weighted sequences provide the information required to allow surgery, radiotherapy (RT) and/or medical therapy to be planned and long-term outcomes to be …
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Blood-Brain Barrier Permeability and Inflammation in Cerebral Small Vessel Disease
… imaging, cognitive and blood markers. Methods: A PET/MR system was used to acquire simultaneous dynamic contrast enhanced MRI with Patlak modelling to measure BBB leakage, and [C11]PK-11195 PET to assess microglia activation. We recruited 20 sporadic SVD patients, 20 monogenic SVD patients …
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Modulating The Unfolded Protein Response as a Therapeutic Target in Alzheimer’s Disease
Dementia can be defined as a disturbance in memory and thinking which interferes with daily life. It is the leading cause of death in the UK, and dementia was estimated to cost the health service in England £24.2 billion in 2015. As such it is one of the major clinical problems of our time. The …