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Showing 1 to 2 of 2 for “"PERM1"”.
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Role of PERM1 in the Development of Insulin Resistance and Diabetic Cardiomyopathy During High-Fat Diet Feeding
… PPARGC1 and ESRR Induced Regulator in Muscle 1 (PERM1) is a striated muscle-specific regulator of mitochondrial bioenergetics, predominantly expressed in skeletal and cardiac muscle. Our group has previously demonstrated that PERM1 is downregulated in both human and mouse failing hearts, and that …
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PERM1-Mediated Metabolic Crosstalk Between the Heart and Skeletal Muscle in Pressure Overload-Induced Heart Failure
… its underlying bioenergetics remain unclear. PERM1, a striated muscle-specific regulator of mitochondrial bioenergetics, is highly expressed in the heart and skeletal muscle. We previously demonstrated that PERM1 is downregulated in failing hearts; however, whether its downregulation also …