Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"PEDV"”.
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Expression and Purification of the C-Terminal Domain of Porcine Epidemic Diarrhea Virus (PEDV) S1 Protein
Porcine Epidemic Diarrhea Virus (PEDV) was first detected in Europe in the 1970s, but did not emerge in the United States until 2013. When it arrived, it ran rampant due to the lack of previous exposure, causing the death of 7-8 million neonatal piglets and $900 million to $1.8 billion in losses to …
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Innate immune evasion and interferon antagonism by porcine epidemic diarrhea virus
… states. The causative agent is PED virus (PEDV), which is an enveloped, positive-sense, single-strand RNA virus in the genus Alphacoronavirus of the family Coronaviridae in the order Nidovirales. The innate immune system is the first line of host defense in response to viral infections. …
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Characterization of virus strain- and pig age-dependence of porcine epidemic diarrhea virus: Implications for vaccine development
Porcine epidemic diarrhea virus (PEDV) is the causative agent of porcine epidemic diarrhea, an enteric disease affecting pigs of all ages that impacts the global swine industry. Although PEDV was first identified in Europe in 1970s and spread to some Asian countries thereafter, PEDV did not emerge …
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Immune response to and pathogenesis of porcine epidemic diarrhea virus
… mortality among pre-weaning pigs. The PED virus (PEDV) is one of several important swine pathogens, which causes significant economic losses to the swine industry. The first outbreak of PED in the United States occurred in 2013. Since then, various studies have been conducted to characterize the …
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Development and Characterization of A Recombinant Orf Virus Vector Expressing the Spike Protein of Porcine Epidemic Diarrhea Virus
… (S) protein of porcine epidemic diarrhea virus (PEDV) was used as our model antigen and the immunogenicity and protective efficacy of a recombinant ORFV expressing the full length S protein of PEDV (ORFV-PEDV-S) was assessed in pigs. The ORFV-PEDV-S virus was generated by homologous recombination …
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Prevalencia y factores asociados al virus de la Diarrea Epidémica Porcina (PEDv) en transporte de cerdos a plantas de beneficio en Colombia
… La forma más rápida de propagación del virus (PEDv) es el transporte de porcinos. Esta enfermedad ingresó a Colombia en el 2014 afectando la producción nacional sin que se conociera el comportamiento epidemiológico en el país. Previamente se había reportado a nivel mundial que la forma más …
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Surveillance of Emerging Livestock Viruses
… outbreaks of porcine epidemic diarrhea virus (PEDV) in Asia and North America highlighted the need for well-validated diagnostic tests for identification of PEDV infected animals and evaluation of their immune status. PEDV was first detected in the U.S. in May 2013 and another swine …
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Vaccine Development Against Porcine Epidemic Diarrhea Virus Utilizing the Hepatitis B Virus Core Antigen Protein
Porcine epidemic diarrhea Virus (PEDV) is a virus effecting swine. It is the cause of disease that manifests with symptoms ranging from depression, to severe dehydration and death. Young piglets are particularly susceptible to the virus, which can reach mortality rates of 100%. Presence of the …
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Development of Virus-like particles (VLPs) Based Vaccines Against Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) and Porcine Epidemic Diarrhea Virus (PEDV)
… (PRRSV) and porcine epidemic diarrhea virus (PEDV) are two of the most prevalent swine pathogens that have impacted the global swine industry for decades. Both are RNA viruses with increasing heterogeneity over the years, making a vaccine solution ever so challenging. Modified live-attenuated …
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Impact of feed additives in swine diets and the effect of corn particle size on metabolizable energy in gestating sows
… to analyze the effect of 5 feed additives on PEDv and PRRSv in a feed matrix. A fourth study was conducted to analyze the effect of corn particle size on digestible and metabolizable energy in gestating sows. In experiment 1, 5 treatments consisting of a control, or the control with 2 levels …
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In vitro inhibition of coronavirus replications
… using porcine epidemic diarrhea virus (PEDV). Cimicifuga rhizome, Meliae cortex, Coptidis rhizome, Phellodendron cortex and Sophora subprostrata radix decreased the MHV production and the intracellular viral RNA and protein expression with EC50 values ranging from 2.0 to 27.5ug/ml. These …
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Understanding the determinants for substrate recognition, regulation of enzymatic activity and the development of broad-spectrum inhibitors of coronavirus 3-chymotrypsin-like proteases
… like pigs (porcine epidemic diarrhea virus, PEDV), cows (bovine coronavirus, BCoV) and poultry (avian infectious bronchitis virus, IBV). Moreover, the global distribution of bats that naturally harbor one or more coronavirus strains heightens the likelihood of emergence of a novel highly …