Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"PDZ-ligand"”.
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Somatostatin Receptor 2 Regulation By C-Terminal Motifs and Pdz Domain Proteins
… density protein/Discs large-1/Zona occludens-1 (PDZ) domain interactions often regulate the trafficking and signaling potential of other GPCRs, we examined the role of the sst2 PDZ ligand and additional C-terminal residues in controlling its intracellular trafficking, signaling, and regulation. …
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The G protein-coupled receptor GPR30 signalosome - A novel G protein-independent mechanism regulating cAMP signaling and receptor trafficking
… constitutively internalizes without any need for ligand binding. (2) GPR30 associates with cytokeratin filaments (3) GPR30 expression in ER+ breast cancer is a favorable prognostic marker for distant-disease-free survival. (4) GPR30 confer some constitutive pro-apoptotic signaling but also readily …