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Showing 1 to 2 of 2 for “"PDZ proteins"”.

  1. Testing Whether MRP4 (a cAMP Efflux Pump) and the Beta 2 Andrenergic Receptor (an Upstream Regulator of cAMP Signaling Pathways

    … second-messenger, cAMP, from cells. MRP4 has a PDZ interacting motif at its carboxy terminal end through which it binds to scaffolding proteins NHERF1 and PDZK1. Previous studies have shown that PDZK1 serves as a scaffold physically coupling MRP4 with the cystic fibrosis transmembrane …

    tenn-hsc Repository record for Testing Whether MRP4 (a cAMP Efflux Pump) and the Beta 2 Andrenergic Receptor (an Upstream Regulator of cAMP Signaling Pathways (opens in a new tab)

  2. Somatostatin Receptor 2 Regulation By C-Terminal Motifs and Pdz Domain Proteins

    … density protein/Discs large-1/Zona occludens-1 (PDZ) domain interactions often regulate the trafficking and signaling potential of other GPCRs, we examined the role of the sst2 PDZ ligand and additional C-terminal residues in controlling its intracellular trafficking, signaling, and regulation. …

    uthsc Repository record for Somatostatin Receptor 2 Regulation By C-Terminal Motifs and Pdz Domain Proteins (opens in a new tab)