Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"PDCD4"”.
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Role of long non-coding RNAs in breast cancer progression
… genes in cis. Further studies on one such NAT, PDCD4-AS1 lncRNA reveal that it positively regulates the expression and activity of the tumor suppressor PDCD4 in TNBC. Both PDCD4-AS1 and PDCD4 show reduced expression in TNBC cell lines and in patients, and depletion of PDCD4-AS1 compromise the …
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RESVERATROL INHIBITS PROSTATE CANCER GROWTH AND METASTASIS BY TARGETING AKT/MICRORNA-21 PATHWAY
… genes, namely programmed cell death 4 (PDCD4) and maspin. Thus, drugs which target <italic>miR-21</italic> for inhibition could provide novel treatment options for metastatic prostate cancer. Resveratrol (3,5,4'-trihydroxystilbene) is a polyphenolic phytoalexin found in high quantities …
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MicroRNA expression and function during porcine oocyte maturation and early embryonic development
… (73.0 ± 5.7%). While no decrease (P = 0.34) in PDCD4 mRNA (a MIR21 target) was observed, inhibition of MIR21 resulted in increased (P < 0.05) PDCD4 protein expression in MII oocytes compared to control MII arrested oocytes. Heat stress during oocyte maturation caused alterations in both MIR21 …
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Identifying circulating biomarkers in a cohort of hypercholesterolaemic patients with statin intolerance from Gauteng, South Africa
… for miR-499a using TargetScan of note is FOXO4, PDCD4 and SOX6, which all are genes associated in pathways related to regulation of smooth and skeletal muscle cell differentiation. Quantitative polymerase chain reaction (qPCR) was used to determine the levels of miR-33a, miR-133a and miR-499a, …