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Showing 1 to 8 of 8 for “"PD149163"”.
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ANTIDEPRESSANT EFFECTS OF THE NTS1 AGONIST PD149163 IN THE FORCED SWIM TEST
… the neurotensin NTS<sub>1</sub> receptor agonist PD149163 and the tricyclic antidepressant drug imipramine on immobility in the forced swim test and on locomotor activity in an open field in mice. PD149163 decreased the total time spent immobile at doses of 0.1 mg/kg and 1.0 mg/kg, without …
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INTRACRANIAL INFUSIONS OF NEUROTENSIN AGONISTS PRODUCE AN ANXIOLYTIC PROFILE IN A RAT ULTRASONIC VOCALIZATION MODEL
… selective neurotensin type 1 receptor agonist PD149163 can attenuate the number of fear-induced 22-kHz ultrasonic vocalizations (USVs) produced by male Wistar rats. A reduction in the number of 22-kHz USV calls is indicative of an anxiolytic effect. The current study used a USV model to …
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ASSESSMENT OF NEUROTENSIN RECEPTOR AGONIST EFFECTS ON FEAR-POTENTIATED STARTLE
… of the NTS<sub>1</sub> receptor agonist PD149163 has exhibited anxiolytic effects in male rats. The present study sought to further evaluate the potential anxiolytic effects of PD149163 by assessing this compound in both male and female C57BL/J6 mice using the fear-potentiated startle …