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Showing 1 to 2 of 2 for “"PCYT1A"”.

  1. Pct1 regulates phosphatidylcholine synthesis in response to changes in surface curvature elastic stress sensed on the inner nuclear membrane

    … phosphocholine cytidylyltransferase α (CCTα or PCYT1A). CCTα has a critical role in lipid metabolism and also has direct clinical relevance as mutations in CCTα result in an interesting spectrum of human diseases, such as lipodystrophy with fatty liver, growth plate dysplasia and cone-rod …

    cambridge Repository record for Pct1 regulates phosphatidylcholine synthesis in response to changes in surface curvature elastic stress sensed on the inner nuclear membrane (opens in a new tab)

  2. The role of macrophage intracellular lipid partitioning in glucose and lipid homeostasis during obesity

    Obesity-associated metabolic disorders are amongst the most prevalent causes of death worldwide. Understanding how obesity leads to the development of the Metabolic Syndrome (MetS) and cardiovascular disease (CVD) will enable the development of novel therapies that dissociate obesity from its …

    cambridge Repository record for The role of macrophage intracellular lipid partitioning in glucose and lipid homeostasis during obesity (opens in a new tab)