Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"PCTK1"”.
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Investigating the regulation of the PCTAIRE-1 protein kinase : a new target of AMP-activated protein kinase and beyond?
PCTK1 is a Cdc2-related protein kinase that is poorly characterised. Several studies have investigated its role and regulation, and have provided some insight into its upstream regulation by PKA/CDK5 phosphorylation. Proposed physiological functions include vesicle trafficking and neurite …
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In Vivo Kinome Screen Reveals Non-Canonical Cdk-Driven Metabolic Adaptation In Brain Metastasis
… across cancer types, I chose to focus on PCTK1 as a potential driver. PCTK1 is expressed during spermatogenesis and neuronal differentiation but reports of its roles in cancer are limited. While overexpression of PCTK1 in MDA-MB-231 cells did not affect proliferation under routine cell …
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Physical and genetical investigation of the Xp11.3 region on the short arm of the human X-chromosome
The pattern of inactivation in the DXS8237E-UBE1-PCTK1 region is of particular interest, since the mechanisms of X chromosome inactivation and the escape from inactivation are, as yet, not fully understood. The inactivation status of the DXS8237E and PCTKl gene differ: the first undergoes normal …