Global ETD Search
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Showing 1 to 2 of 2 for “"PCTAIRE-1"”.
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Investigating the regulation of the PCTAIRE-1 protein kinase : a new target of AMP-activated protein kinase and beyond?
PCTK1 is a Cdc2-related protein kinase that is poorly characterised. Several studies have investigated its role and regulation, and have provided some insight into its upstream regulation by PKA/CDK5 phosphorylation. Proposed physiological functions include vesicle trafficking and neurite …
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Roles of Myocardin-Related Transcription Factors in Muscle and Brain
… the MRTF/SRF pathway in the regulation of the Pctaire-1/Cdk5 kinase cascade to govern actin dynamics. I conclude that MRTFs function as essential coregulators of SRF to control actin dynamics during neuronal development via the Cdk5/Pctaire-1 kinase cascade. I also explore the role of MRTF-A …