Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"PCP signaling"”.
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Fgf4 and Wnt5a/Pcp Signaling Promote Limb Outgrowth by Polarizing Limb Mesenchyme
… between FGF and Wnt/Planar cell polarity (PCP) signaling in establishing cell polarity as a mechanism for outgrowth. By implanting beads into embryonic limbs and lateral plate mesoderm, we established that FGF activates Wnt5a in a gradient fashion. Once it was established that Wnt5a was …
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The Role of PRICKLE1 in the Regulation of Uterine Structure and Physiology
… to non-canonical Wnt/Planar Cell Polarity (PCP) signaling, regulating cell adhesion, migration, and differentiation. Dysregulation of PRICKLE1 is implicated in various diseases, including cancer and epilepsy. In UL, PRICKLE1 is proposed to be essential for REST nuclear localization, with its …
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The extreme anterior domain coordinates brain and craniofacial development
… suggests that the EAD affects beta-catenin Wnt signaling over a range of 800 microns. By affecting the growth of both the brain and neural crest-derived cartilage, the EAD determines the overall size of the head. Second, the EAD synchronizes neural crest migration and the formation of two …
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Charakterisierung des Vertebraten-Gens four-jointed x1 (fjx1) und Analyse des planaren Zellpolaritätssignalwegs (PCP-Signalweg)
… untersuchten planaren Zellpolaritätssignalweg (PCP-Signalweg). Über das in der Maus identifizierte homologe fjx1 Gen ist dagegen vergleichsweise wenig bekannt. Ziel dieser Arbeit war daher die nähere Charakterisierung von fjx1 sowie die Identifizierung möglicher Interaktionspartner. Durch RNA in …