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Showing 1 to 3 of 3 for “"PCNT"”.

  1. Vascular Disease Pathogenesis In Smooth Muscle Dysfunction Syndrome and Majewski Osteodysplastic Primordial Dwarfism Type Ii

    … to homozygous loss-of-function mutations in <em>PCNT</em>, which lead to primordial dwarfism and early onset occlusive vascular disease, including moyamoya disease and coronary artery disease. We examine the pathogenic mechanisms of vascular disease in MOPDII using a novel SMC-specific …

    uthsc Repository record for Vascular Disease Pathogenesis In Smooth Muscle Dysfunction Syndrome and Majewski Osteodysplastic Primordial Dwarfism Type Ii (opens in a new tab)

  2. Estudio molecular de pacientes colombianos afectados por enanismo esencial

    … estudio se investigaron variantes en el gen PCNT debido a que presentaban hallazgos clínicos compatibles con el síndrome MOPD II (enanismo esencial osteodisplásico microcefálico tipo II). Posteriormente, se amplió el estudio con una secuenciación de exoma en una paciente con variantes …

    rosario Repository record for Estudio molecular de pacientes colombianos afectados por enanismo esencial (opens in a new tab)

  3. Mapping the cell cycle-dependent centrosomal interactome

    … was fused with centrosomal proteins Centrin 2, PCNT and Cep192 to detect the centrosome interactome. The cell cycle-dependent interactome of the centrosome was mapped by combining proximity biotinylation and a reversible drug-mediated cell cycle synchronisation method based on the CDK4/6 …

    edinburgh Repository record for Mapping the cell cycle-dependent centrosomal interactome (opens in a new tab)