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Showing 1 to 2 of 2 for “"PCM1"”.
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CHARACTERISATION OF A NOVEL SPINDLE DOMAIN IN MAMMALIAN MEIOSIS
… including Pericentriolar material 1 protein (PCM1). This domain was distinct from spindle microtubules and the acentrosomal microtubule organising centres (aMTOCs). Initial characterisation focused on PCM1, the main centriolar satellite scaffold protein in somatic cells. Depletion of PCM1 …
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Towards the understanding of pericentriolar satellite biology
… affinity purification of a key PS component, PCM1. To eliminate contamination by centrosomes, the PS proteome was determined from wild-type cells as well as from two cell lines genetically engineered to lack centrosomes. Mass spectrometry identified 170 PS components including most of the …