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Showing 1 to 7 of 7 for “"PCEF"”.
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Optimization of photonic crystal enhanced fluorescence by excitation laser angle scanning
Photonic crystal enhanced fluorescence (PCEF) has been demonstrated as an effective means for amplifying the excitation provided to surface-bound fluorescent molecules while simultaneously enhancing fluorescence emission collection efficiency. Optimal coupling of a fluorophore-exciting light source …
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Highly sensitive biosensors using photonic crystal enhanced fluorescence
… photonic crystal enhanced fluorescence (PCEF) was used for disease biomarker dissertation. We applied PCEF to multiplexed microspot immunoassays for detection of allergen-specific antibodies. The PCEF system was able to detect low concentrations of Fel d1 specific IgE ~0.02 kU/L, which is …
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Next generation instrumentation for photonic crystal biosensors: a passage to early detection of cancer
… using photonic crystal enhanced fluorescence (PCEF) instrumentation as the best way to achieve this goal. We introduce a model for predicting enhanced fluorescence (EF) performance of a photonic crystal (PC) in the context of a given set of instrument parameters as well as insights into …
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Designing, construction and analysis of line-scanning detection instrument for photonic crystal enhanced fluorescence
… for photonic crystal enhanced fluorescence (PCEF) based on the bench-top line-scanning detection instrument. From the computational model, we concluded that of the several parameters in the instrument, the quantum efficiency and dark current of the camera are very critical for the detection …
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Study and development of plasmonic biosensors for biomedical applications
… and describing PC enhanced fluorescence (PCEF), this dissertation is mainly concerned with the study and development of highly effective surface-enhanced Raman scattering (SERS) substrates and their potential applications in detection and identification of intravenous drugs. Chapter 1 …
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Sensitive microarray-based biomarker detection using photonic crystal enhanced fluorescence and label-free imaging
… the development of a PC enhanced fluorescence (PCEF) based detection platform for POC diagnostics. biomarkers implicated in cancer were detected at concentrations as low as 0.1pM and 0.6pM, respectively. This work lays the foundation for the development of a PC enhanced fluorescence (PCEF) based …
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Photonic crystal enhanced light emitters and their use in improving cancer screening and disease progression monitoring
Screening for and monitoring the progression of cancer remains a complex task in medicine today, further complicated by the variety of both cancer types and treatments. Each patient's response to treatments and cancers is unique, calling for a personalized approach to healthcare. Early detection …