Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"PAX genes"”.
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The role of pax genes in vertebrate segmentation
Pax genes are involved in a range of processes in the developing embryo. Pax3 and Pax7 in particular are associated with the paraxial mesoderm, especially the development of the myogenic lineage. However, recent studies have suggested that Pax3 and Pax7 may have earlier, morphogenetic roles in the …
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Generation of A L. Hesperus embryonic cDNA library for the isolation of genes involved in early pattern formation
… other metazoans primarily use two families of genes called Hox genes and Pax genes to regulate embryogenesis. Because of the high evolutionary conservation of Hox and Pax proteins, I hypothesize that arachnids also use this system to organize their body pattern. To enable studies of the Westem …
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An investigation of the mechanism of PAX7 mediated oncogenesis via in silico and in vitro biology
The Pax gene family appears to have evolved by a combination of gene duplication and / or genome duplication events over a long period of evolutionary time. The highly conserved paired box sequence within the Pax genes encodes a paired DNA binding domain, indicating that the Pax proteins are …
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GENETIC CONTROL OF EYE AND CENTRAL NERVOUS SYSTEM DEVELOPMENT
… by haploinsufficiency of transcription factor PAX6, is characterized by complete or partial iris hypoplasia with associated foveal hypoplasia. Brain imaging performed in patients heterozygous for PAX6 mutations often reveal absence of the brain anterior or posterior commissure, absence of the …
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Strukturelle und funktionelle Untersuchung der Promotorregionen der menschlichen PAX3-, PAX6- und PAX7-Gene: Bedeutung von Polymorphismen für schizophrene Erkrankungen
… potentiell relevanter Entwicklungsgene. Die Pax-Gene sind Mitglieder einer Familie der Transkriptionsfaktoren, die sowohl mehrere Schritte in der Embryogenese als auch Aufrechterhaltung des Differenzierungszustandes der Zellen einiger adulten Gewebe kontrollieren. Im Rahmen dieser …