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Showing 1 to 1 of 1 for “"PARP trapping"”.
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Receptor Tyrosine Kinases-Mediated Acquired Parp Inhibitor Resistance In Breast Cancer
… Small molecule poly(ADP-ribose) polymerase (PARP) inhibitors (PARP-is) have been approved for clinical use in treating breast cancer and ovarian cancer patients bearing DDR-deficient tumors with mutations in breast cancer susceptibility genes (<em>BRCA</em><sup>m</sup>). However, accumulating …