Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"PAKs"”.
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A NOVEL BRAF SIGNALING CASCADE THROUGH p-21 ACTIVATED KINASES REGULATES THYROID CANCER CELL MOTILITY
… of p-21 activated kinase (PAK) signaling. When PAKs are activated, they redistribute to the leading edge of a cell and direct the formation of lamellopodia and motility. In addition, PAK overexpression has been discovered and implicated in the progression of a number of other solid tumors, …
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Effects of AFEX Pretreatment, Denisifcation and Storage on Ethanol Yields of Corn Stover, Switchgrass and Prairie Cordgrass
… application. Concerning densification into PAKS, results were substrate specific. Sugar and ethanol yields from PCG and SG were negatively impacted by densification. Glucose yields dropped from 62% to 53%, and ethanol yields fell from 46% to 38% in non-densified substrates versus PAKS. …
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Regulation of Myo5p function by phosphorylation
… cytoskeleton. In vitro, p21-activated kinases (PAKs) can phosphorylate a single serine in the myosin-I head domain, referred to as TEDS site, thereby activating the myosin-I ATPase. This work demonstrates that phosphorylation of the Myo5p TEDS site is required for two myosin-I in vivo functions …
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Characterization of a novel cellulose biosynthesis inhibitor, CBI28, in Gluconacetobacter xylinus
… using methanol and Waters Oasis HLB SPE-Paks. Samples were separated and detected using the Ultra Performance Liquid Chromatograph-Mass Spectrometer/Photo Diode Array. Putative mutants were isolated but did not survive for further study. An ion with the expected mass of a CBI28-Biotin …
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Evaluation of outbound operations improvement projects for distribution centers
… new packaging options such as envelopes and paks, creating an optimal box selection strategy, and adopting a custom box-making system to the current process flow. For each option a systematic evaluation method is established, containing the analysis on financial returns, implementation …
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The role of PAK6 in HGF-induced prostate cancer cell migration
… their effector proteins, p21-activated kinases (PAKs), which are a family of mammalian serine/threonine protein kinases. PAK6, a PAK family member, is over-expressed in prostate cancer but little is known about its function in cells. This project investigated the potential role of PAK6 downstream …
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Invadopodia Formation in Breast Cancer
… with effector proteins p21-activated kinases (PAKs) are known to regulate actin cytoskeletal dynamics. Indeed, PAK1/2 are over-expressed in breast cancer however the role of PAK1/2 in invadopodia formation has not been fully investigated.<br/><br/>This project sought to investigate the …
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Physics and engineering aspects of South Africa's proposed dry storage facility for spent nuclear fuel
… aspect of the dry cask storage facility at MV Paks in Hungary should also be employed at Koeberg to allow for more storage. This will cater for additional casks that may need to be stored if more nuclear power plants are procured in the future. South Africa’s air traffic around the Western Cape …
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Predictive Modeling of Organic Pollutant Leaching and Transport Behavior at the Lysimeter and Field Scales
Soil and groundwater pollution has become a global issue since the advent of industrialization and mechanized agriculture. Some contaminants such as PAHs may persist in the subsurface for decades and centuries. In a bid to address these issues, protection of groundwater must be based on the …