Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"PAC1R"”.
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Pituitary adenylate cyclase-activating polypeptide regulates excessive alcohol consumption
… demonstrate that the dysregulation of the PACAP/PAC1R system, specifically in the NAcc core, promotes excessive drinking and alcohol-seeking behavior, indicating that blockade of the PACAP/PAC1R system may represent a novel target for alcohol addiction.
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Activation mechanisms of non-class A G protein-coupled receptors
… and Pituitary Adenylate Cyclase 1 receptor (PAC1R), and fungal Class D receptor STE2, using large-scale all atom unbiased molecular dynamics simulations. To overcome the limitations associated with traditional MD simulations, we employ multiple adaptive sampling strategies to sample rare …