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Showing 1 to 2 of 2 for “"PAC1 cells"”.

  1. Identification of RBPMS as a smooth muscle master splicing regulator via association of its gene with super-enhancers

    … splicing regulator in vascular smooth-muscle cells (SMCs). RBPMS is strongly downregulated during SMC dedifferentiation and is responsible for nearly 20% of the AS changes during this transition as indicated by mRNA-Seq of rat PAC1 cells with RBPMS-manipulated levels. RBPMS overexpression also …

    cambridge Repository record for Identification of RBPMS as a smooth muscle master splicing regulator via association of its gene with super-enhancers (opens in a new tab)

  2. Identifying sm22 as a key player in arterial diseases

    … in triplicate using siRNA in a VSMC line, PAC1, followed by downstream experiments 3 days after transfection. Results : Sm22<sup>-/-</sup> mice developed both enhanced arterial inflammatory response and prominent medial chondrogenesis along with remarkable NF-ΚB activation compared to their …

    wayne-thes Repository record for Identifying sm22 as a key player in arterial diseases (opens in a new tab)