Global ETD Search
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Showing 1 to 3 of 3 for “"PABP1"”.
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Isolation and characterization of Hupf1-containing protein complexes and their role in nonsense-mediated mRNA decay
… proteins Hupf2 and Poly(A)-binding protein 1 (Pabp1). Using size exclusion chromatography it was shown that the majority of Hupf1 occurs as a monomer, but two complexes of distinct composition could be isolated. Further analysis of affinity purified Hupf1-containing complexes by Western Blot …
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Investigating the role of PABPC5 in mouse physiology
… been identified, some widely expressed (e.g., PABP1 and PABP4) while others are limited to specific tissues and developmental time points (e.g., ePABP). The best described member, PABP1, has been found to be essential for the translation of messenger RNA to protein according to in vitro data. …
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Role of PABP4 in intrauterine growth restriction
… protein (PABP) family of RNAbinding proteins, PABP1 and PABP4, are widely expressed in a range of adult tissues. PABP1, the prototypical family member, has been intensively characterised as central regulator of both global and mRNA-specific translation and mRNA turnover in vitro and in cell …