Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 68 for “"P50"”.
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ROLE OF P50 NF-KB IN MACROPHAGE MIGRATION
… such as a massive accumulation of the p50 NF-B homodimer in the nucleus and the incapacity to express strong inflammatory programs (eg. impaired TNF production) in response to inflammatory signals such as LPS (tolerance). Our recent study has described that both TAM and LPS-tolerant …
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P50 Sensory Gating: Impact of High Vs Low Schizotypy Personality and Smoking Status
… 4) Individuals with schizotypy will show greater P50 deficits in the left hemisphere, and smoking can enhance this asymmetry (left greater than right). From 613 online-surveyed participants, 39 (18 men) right-handed undergraduates (Mean age = 18.87) were selected to represent four groups: High and …
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Tetrachlorobiphenyl metabolism, toxicity, and regulation of cytochrome P50 expression in a marine teleost fish
The effects of 3,3',4,4'-tetrachlorobiphenyl (TCB) were examined in the marine fish scup (Stenotomus chrysops), focusing on the interactions between TCB and the CYP 1 A 1 enzyme system. A low TCB dose (0.1 mg/kg) elicited strong and sustained induction of hepatic CYP1A1 mRNA, protein content, and …
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Mild Traumatic Brain Injuries and Their Implications on Changes in Event Related Potentials: A look into Visual Gating (P50)
… (control and concussed) as seen by the P50 ERP after the presentation of our visual stimulus, which is dependent on the Order the stimulus is presented (1<sup>st</sup> or 2<sup>nd</sup>). Our findings show that those who have suffered a concussion show a difference in the ability to …
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An investigation into the role of Bcl-3 in toll-like receptor signalling
… of homodimers of the NF-κB subunit, p50. Through stabilisation of inhibitory p50 homodimers, Bcl-3 negatively regulates NF-κB dependent inflammatory gene transcription following TLR activation. Firstly, we investigated the nature of the interaction between Bcl-3 and p50 and using …
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A Neurophysiological Investigation of Sensory Gating in Adults with Down Syndrome: Relationships with Age, Cognition, and Dementia
… In typically developing (TD) individuals, the P50 event-related potential serves as a marker of amyloid-related neurophysiology. Contrary to patterns in TD individuals, in Down syndrome (DS), the frontal cortex is more vulnerable to neuropathology than the temporal cortex. The coordination of …
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Expression des Transkriptionsfaktors NF-kappaB in Zellen des Hodgkin-Lymphoms und des großzelligen anaplastischen Lymphoms
… Zelllinien wurden die NF-kappaB-Faktoren p50 und p65 konstitutiv nukleär exprimiert. In den HD-Zelllinien fand sich zusätzlich konstitutives c-Rel, in den LCAL-Zelllinien dagegen konstitutives RelB. Diese vier Faktoren zeigten auch in den jeweiligen Zellen konstitutive Bindungsaktivität. …
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Control of major histocompatibility Class I antigen expression in adenovirus transformed cells.
… of CRE1 factors, likely to represent NF-kappaB (p50/p65 heterodimers) and H2TF1 (p50 homodimers), was higher in cells expressing Ad2 or Ad5 E1A than those expressing Adl2 E1A. Western blotting using an antibody prepared to the p50 subunit of NF-kappaB did not show a difference in levels of this …
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Sensory gating and sensorimotor gating in psychiatric disorders sharing attention deficits
… of sensorimotor gating, and suppression of the P50 auditory event-related potential (AEP) in a condition-test paradigm (P50 suppression), considered as a form of sensory gating. While sensory gating and sensorimotor gating have been proposed to be endophenotypic biomarkers for schizophrenia …
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Glucan synthase of Phytophthora sojae
… In contrast, a full length cDNA (named Ps-P50) was cloned, using the oligonucleotides derived from the 50 kDa protein (P50). The deduced amino acid sequence of Ps-P50 cDNA contains sequence motifs homologous to the peptides sequenced from P50. This cDNA encodes a protein with a molecular …
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Roles of NF-kB in spinal cord injury pathophysiology
… NeuN co-localization with NF-kB p65 and p50 revealed neuronal increases up to 24 hours, especially in the nucleus of cells, supporting activation of NF-kB p50/p65 and p50/p65-induced apoptotic gene transcription after SCI. Western blots of p65 and p50 showed no changes in their protein …
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Synchronized Gamma Oscillations Underlying Mid-latency Auditory Evoked Potentials: Assessment of Effects of Psychopharmacologically Active Components of Tobacco
… effects of smoking cigarettes on sensory gating, P50 and stimulus-bound gamma band (32-48 Hz) oscillations were examined in two paradigms: paired-tone and oddball. During a paired-tone paradigm, our previous work (Crawford, McClain-Furmanski, Castagnoli, & Castagnoli, Neuroscience Letters …
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Percentiles de circunferencia de cintura en escolares de Bogotá, Colombia Estudio FUPRECOL
… Se calcularon los percentiles (P3, P10, P25, P50, P75, P90 y P97) y curvas centiles según sexo y edad. Se realizó una comparación entre los valores de la circunferencia de cintura observados con estándares internacionales. Resultados: De la población general (n=5.921), el 57,0% eran chicas …
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Palm oil shell aggregate as cool pavement by replacing fine aggregate
… (P10), 20% (P20), 30% (P30), 40% (P40) and 50% (P50) were mixed into asphalt pavement for subsequent experiment and compared with control sample (CS). The result demonstrated POSA’s particle density value at 1.6mg/m3 and specific gravity value of 1.6, fulfil the minimum requirement by AASHTO …
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Assessing safety margins and hydraulic strategies in Restionaceae: evaluating xylem hydraulic traits in two Elegia species
… margin (difference between xylem vulnerability (P50; MPa) to cavitation and point at which stomata are considered closed (turgor loss point; MPa)) displays the tolerance margins based on plant physiological capacity. Restionaceae have shown extensive evidence of hydraulic niche segregation and …
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Differences of DNA-Transcription Factor Interactions Following Chromium Exposure
… sequence of êB DNA on the binding affinity of p50BD was determined using a 22-mer and a 30-mer double-stranded DNA oligonucleotide containing the NF-êB binding site. The addition of a carboxyl moiety at position 8 on guanine (creating 8-oxoguanine) was observed to change the binding affinity of …
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Differences of DNA-Transcription Factor Interactions Following Chromium Exposure
… sequence of êB DNA on the binding affinity of p50BD was determined using a 22-mer and a 30-mer double-stranded DNA oligonucleotide containing the NF-êB binding site. The addition of a carboxyl moiety at position 8 on guanine (creating 8-oxoguanine) was observed to change the binding affinity of …
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Regulation of VEGFR-3 expression and lymphangiogenesis in normal and inflamed tissues
… characterize the lymphatic phenotype of NF-κB p50 knockout mice. To begin testing these hypotheses, we used a mouse model of peritonitis to characterize induction of lymphangiogenesis and expression kinetics of NF-κB, Prox1 and VEGFR-3. In vivo time-course analysis of inflammation-induced …
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Bloqueio adenosinérgico e filtro sensorial
… com enfoque particular no paradigma do P50, uma técnica eletroneurofisiológica de extremo valor para a investigação da neurobiologia básica subjacente aos defeitos de processamento sensorial que caracterizam algumas doenças mentais, e mais particularmente a esquizofrenia, sobre a qual …
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Influence of a Nicotinic Treatment on Auditory Sensory Processing in Schizophrenia
… stimuli, as measured by suppression of the P50 auditory ERP and (b) the ability to facilitate responses to infrequent but salient (deviant) stimuli, as measured by the mismatch negativity (MMN) ERP. Acknowledging the baseline-dependent effects of nicotine, each of the four investigations …
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