Global ETD Search
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Showing 1 to 4 of 4 for “"P2X3"”.
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ATP, TRP channels and airway neuronal sensitisation
… a potent tussive agent acting via the purinergic P2X3receptor on airway nerves.<br/><br/>In chapter 3 it was hypothesised that TRPV2 is expressed in PBECs and that ATP is released from PBECs following mechanical stimulation; furthermore, it was hypothesised that TRPV2 has a role in ATP release. …
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Molekulare und histologische Untersuchungen zur gustatorischen Fettwahrnehmung des Menschen
… Hilfe einer vorherigen Intervention mit einem P2X3 /P2X2/3-spezifischen Antagonisten an der Maus als Modellorganismus im Kurzzeit-Präferenztest untersucht. Es zeigte sich weder eine Beeinträchtigung der Wahrnehmung einer Fettsäurelösung, noch einer zuckerhaltigen Kontrolllösung, wohingegen die …
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PURINERGIC TRANSMISSION IN MIGRAINE: ROLE OF P2Y RECEPTORS IN THE SPINAL-TRIGEMINAL SYSTEM IN VIVO AND IN VITRO
… TG sensory neurons mainly express functional P2X3 receptors, while SGCs are highly responsive to P2Y-agonists (i.e., ADP, UTP, and UDP). Moreover, exposure to the pro-inflammatory agent BK significantly modified P2X3 receptor function in a biphasic way, with an upregulation or a reduction of …
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Pharmacological targets for treatment of retinal neurodegenerations: new perspectives [Nuove prospettive sui target farmacologici per il trattamento della neurodegenerazione retinica]
… Inoltre, i recettori purinergici ionotropici P2X3 e P2X4, insieme agli enzimi codificati da CYP2C8, LDHA e MAOB potrebbero essere degni di ulteriori indagini sperimentali per la mancanza di studi preclinici e clinici legati ad essi. In più, si è evidenziato il coinvolgimento di diversi geni …