Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"P2RY12"”.
-
DNA Methylation and Gene Expression of P2RY12 in a Multi-Ethnic Cohort
… DNA methylation at cis acting CpG sites and P2RY12 gene expression.
-
Molecular genetic mechanisms of eosinophil activation in aspirin-exacerbated respiratory disease : Genetic mechanisms of eosinophil activation
… eosinophils via dysregulation of IL5, IL5RA and P2RY12 genes may play an important role in the pathogenesis of asthma and AERD. We purposed to identify a potential association of IL5, IL5RA and P2RY12 genetic polymorphisms in the susceptibility to asthma and AERD in a Korean population. Materials …
-
Downregulation of miR-10a-5p as a Potential Therapeutic Target to Improve the Detrimental Effects of Post-stroke Social Isolation
… There was no statistical significance seen in P2RY12 expression in microglia of male mice but the experimental groups seemed to follow a similar trend in expression as Tmem119 expression in microglia in males. In females Tmem119 expression and P2RY12 expression in microglia was similar and …
-
Human leptomeninges; inflammatory roles in motor neuron disease, and their potential in gene therapy
… in the intact explants expressing IBA1 and/or P2RY12, or PDGFRβ and/or lectin. Specific culture paradigms were used to explore culture-driven effects on the tissue model. Tissue health and cell populations within were unchanged after 5 weeks in culture. Based on the evidence of meningeal …
-
The Transcriptional Profile of Microglia: From Brain to Dish
… marker genes and transcription factors, such as P2RY12 and SALL1, when compared to primary cells. Using gene-set enrichment analysis tools, I have shown that many of the genes with higher expression in primary cells can be linked to neuronal processes such as CNS myelination. Data from the third …