Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 58 for “"P25"”.
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Molecular modeling and SAR studies of CDK5/p25 selective inhibitors
… p35 is cleaved by calpain to a shorter protein p25, which in turn hyperphosphorylates Tau, forms neurofibrillary tangles and causes AD. CDK5 deregulation is also indicated in other neurodegenerative diseases, such as Huntington's chorea, stroke, Parkinson's disease, amyotrophic lateral …
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Design and Synthesis of Novel Benzimidazoles and Aminothiazoles as Small Molecule Inhibitors of CDK5/p25
… and biological evaluation of novel CDK5/p25 small molecule inhibitors. Cyclin dependent kinase 5 (CDK5) is a proline directed serine/threonine kinase which plays an important role in the pathology of Alzheimer's disease (AD). CDK5/p25 has been implicated in hyperphosphorylation of tau …
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The photo-oxidation of benzyl alcohol over TiO2 and Pt TiO2 and the effect of reaction conditions
… of benzyl alcohol over titanium dioxide (Degussa P25) in toluene as a solvent, were investigated. The reaction is photoinduced, as no reaction was observed under dark conditions, but a conversion of benzyl alcohol of ca. 20% was recorded under ultraviolet and of ca. 9% under visible irradiation …
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An investigation of developing and developed turbulent flows through annuli.
… Basement, West Bldg. / Call Number: Thesis1973 .P25. Source: Dissertation Abstracts International, Volume: 62-13, Section: A. Thesis (Ph.D.)--University of Windsor (Canada), 1973.
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The epidemiology of ovine progressive pneumonia (ovine lentivirus): Diagnosis, risk factor analysis, and production effects in sheep at the United States Meat Animal Research Center
… proteins (transmembrane (TM), major capsid P25, and matrix P16) were produced in E. coli and purified for use as antigen for anti-OLV antibody detection by indirect enzyme-linked immunosorbent assay (ELISA). In a comparison of recombinant TM, P25, and P16 ELISAs, a whole-virus ELISA and the …
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Mechanisms of DNA double strand break-mediated neurotoxicity in neurodegenerative disease
… we characterize DSB-bearing neurons from the CK-p25 mouse model of neurodegeneration using single-nucleus, bulk, and spatial transcriptomic techniques. DSB-bearing neurons enter a late-stage DNA damage response marked by NFκB-activated senescent and antiviral immune pathways. In humans, …
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Fotocatalisadores para degradação de compostos tóxicos da indústria do petróleo e petroquímica
… g-C3N4/TiO2 (com 25% de g-C3N4), g-C3N4 e TiO2 P25 comercial para degradar a quinolina. Os catalisadores heteroestruturados foram preparados utilizando TiO2 P25 comercial e g-C3N4 obtido a partir da policondensação térmica da ureia. Os catalisadores foram caracterizados por análises …
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Design, construction and commissioning of an automated optical fibre catalyst coating process for use in photocatalytic reactor systems
… a solgel suspension or a slurry containing P25 (TiO2). A multi-step optical fibre coating process was developed to achieve the desired coated optical fibre as a product. It consists of 6 major units that process raw (polymer-coated) optical fibre into catalyst coated optical fibre. The steps …
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Regulation of Phosphorylation of PPARγ by CDK5 in Obesity
… while obesity promoted cleavage of p35 to p25 thereby enhancing CDK5 phosphorylation of PPAR? (Choi et al 2010). However the sequence surrounding Ser273 is not a CDK5 consensus, therefore I have analysed PPAR? phosphorylation more carefully. I mutated Ser273 on PPAR? to alanine and compared …
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Remediation of endocrine disruptor in contaminated water through advanced oxidation processes
… como fotocatalizadores fueron ZnO, TiO2 P25, TiO2 Alfa Aesar y TiO2 vlp 7000, y el aceptor de electrones fue Na2S2O8. Del mismo modo, se procedió a la caracterización de cada uno de los semiconductores empleados. Las variables operacionales en los distintos ensayos de fotodegradación …
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Caracterización clínica de pacientes con trastornos del espectro de neuromielitis óptica en la ciudad de Bogotá - Colombia
… (18 mujeres, mediana de edad de 53.5 años; P25-P75= 40.5-58.0, todos de raza mestiza). La mediana de edad de inicio fue de 46.5 años (P25-P75=34.2-54.0), la mayoría de los pacientes tuvo manifestaciones clínicas a nivel sensitivo (n=22) y motor (n=20), en seis (n=6) pacientes se identificó …
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Identifizierung und Charakterisierung neuer Isotypen des Hüllprotein-Komplexes Coatomer
… eingebaut wird. Die Coat-Rezeptoren p23, p24 und p25 sind in der Lage, Coatomer zu binden. Für p23 wurde bereits eine direkte Interaktion mit der g-Untereinheit von Coatomer nachgewiesen. Daher wurde die Affinität der zytoplasmatischen Domänen von p24-Familienmitgliedern und Wbp1, einem …
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Selective oxidation of methane in a trickle bed reactor over a platinum-based catalyst
… were performed on platinum impregnated TiO2(P25) and TiO2(rutile) in the newly constructed trickle bed reactor at 220 °C and 30 bar. The inlet partial pressures of methane and oxygen were kept constant at 0.5 bar and 1.5 bar, respectively, while the feed rate of liquid water was varied from 0 …
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Identification of the impact of generalized seizures on brain electrical activity during development using EEG correlates
… v časných postnatálních stadiích (P12, P15, P25) s významnými rozdíly specifickými pro pohlaví, s vyšší frekvencí záchvatů u samců. Navíc, absence "tiché fázi" svědčí o rychlém rozvoji chronické epilepsie po flurotylem indukovaných opakovaných záchvatů. Spektrální analýza EEG dat ukázala …
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Design and Synthesis of Benzimidazoles as CDK5 Inhibitors and Progress toward the Total Synthesis of Tubulysin D
… tau. Selective inhibition of the CDK5/p25 complex may be a useful component for Alzheimer's disease therapy. Benzimidazole based analogs of the known non-selective CDK5 inhibitor (R)-Roscovitine were designed. Synthesis of 6-benzyl substituted benzimidazole analogs was developed and two …
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Development of Photocatalytic Reactor Technology for the Production of Fermentable Sugars
… production rates using coumarin as a probe. TiO2 P25 was the photocatalyst that was found to have the highest OH radical production rate of 35.6 μM/hr, followed by Pt-C3N4 (0.88 μM/hr) and WO3 (0.28 μM/hr). LaCr-SrTiO3, Cr-SrTiO3 and yellow TiO2 did not produce any OH radicals due to their …
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Développement d'un photocatalyseur à base d'oxyde de titane pour l'élimination de polluants et de bactéries en milieu aqueux
… part, par greffage sur le catalyseur Degussa P25 et d’autre part, in situ dans la matrice de xérogels de TiO2. Le greffage des porphyrines ne permet pas l’activation du catalyseur Degussa P25 sous lumière halogène. Par contre, l’introduction in situ des porphyrines permet l’activation du TiO2 …
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Android Phone Controlled Beagle Board Based PSCR in a Dynamic Spectrum Access Environment
… a new feature that enables interoperation with P25 (CPFSK modulation) protocol based radios is added. In this effort of porting the PSCR to Beagle Board my contributions are the following (i) communication protocol between the Beagle Board and the Nexus One (ii) PSCR control application on the …
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Polymeric Adsorption of Estrone from Water and Photocatalytic Degradation by Zinc Oxide
… activity to the benchmark Aeroxide P25® TiO2 photocatalyst, providing up to three times faster photocatalytic degradation for estrone. Complete decomposition of estrone in a 600 μg/l solution was observed after 10 min of exposure under an 18W UVA lamp using 0.5 g/l ZnO photocatalyst. …
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The aerobic, water-assisted selective oxidation of methane over platinum-based catalysts
… titania supported catalysts (TiO2, rutile and P25), which deactivated with time, due to deposition of formaldehyde polymeric species. In total, the supports investigated were alumina, carbon, the rutile phase of titania and P25 (a mixture of rutile and anatase). The catalytic activity was in …
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