Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"P19 cells"”.
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SF-1, BUT NOT DAX-1, PREVENTS P19 CELLS FROM DIFFERENTIATING TO EITHER TROMA-1 OR TUJ1 POSITIVE CELLS UPON RA-TREATMENT
… factors (PBX) mRNA and protein levels in P19 cells prevents them from differentiating to either endodermal or neuronal cells. This suggests that PBX is an important regulator of RA-induced differentiation of P19 cells. A microarray analysis was performed to identify PBX regulated genes, …
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Sonic hedgehog induces Motor Neuron Differentiation in P19 Embryonic Carcinoma Cells
… we utilized embryonal carcinomal P19 cells as an in vitro model system. We overexpressed Shh in P19 cells and investigated it’s effects on proliferation and differentiation of P19 cells., P19/Shh, P19 cells overexpressing Shh, proliferated at higher rates than normal P19 cells even …
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The roles of the retinoic acid receptors in growth, differentiation and development.
… retinoic acid (RA) induced differentiation of P19 cells. I used mutant RARs to block the normal differentiation of these cells and then analyzed the possible mechanisms by which these mutants are able to exert such effects. My results indicate that overexpression of a dominant negative RAR …
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The transcriptional regulation of skeletal muscle progenitor cell fate
… was able to induce the entire myogenic program. Cells overexpressing Sox15 show elevated levels of genes that inhibit differentiation and promote proliferation, which coincides with the lack of progression past the muscle precursor stage. These results demonstrate that Sox15 and Sox7 have …
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Role of Sonic Hedgehog in Development of the Central Nervous System
… promote cell cycle progression of embryonic stem cells as well as adult neural stem/progenitor cells. However, it has not been elucidated how Shh induces neural induction during early development of nervous system. To elucidate the role of Shh in neural induction, we used a pluripotent embryonal …