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Showing 1 to 1 of 1 for “"P-site inhibitors"”.

  1. Characterization of Selective Inhibition of Adenylyl Cyclase Activity By Small Molecule Inhibitor Nky80

    … and there are currently no isoform selective AC inhibitors in clinical use.</p> <p>P-site inhibitors inhibit AC directly at the catalytic site, but with an uncompetitive or noncompetitive mechanism. Due to this mechanism and nanomolar potency in cell-free systems, attempts at ligand-based drug …

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