Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"P-Glycoprotein inhibition"”.
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Design and Synthesis of Cellulose Ether Derivatives for Oral Drug Delivery
… derivatives for applications including ASDs, P-glycoprotein inhibition, antimicrobial, coating, and other biomedical applications.
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The effects of various combinations of different classes of anticancer drugs and tyrosine kinase inhibitors on the human MCF-7 and triple-negative MDA-MB 231 breast carcinoma cell lines
… survival. It is often overexpressed in TNBC. P-glycoprotein (P-gp) is a transmembrane glycoprotein responsible for active transport of substances across the cell membrane out of a cell. It functions as an efflux pump and is overexpressed in many cancer cells. The altered expression of both EGFR …
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Evaluation of Novel Efflux Transport Inhibitor for the improvement of drug delivery through epithelial cell monolayer
… of multidrug resistance proteins such as P-glycoprotein (P-gp). P-gp removes substances out back from the brain to the blood before they reach to the brain. So the barrier is impermeable to many compounds such as amino acids, ions, small peptides and proteins, making it the most challenging …
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P-glycoprotein and membrane permeability as determinants of xenobiotic bioavailability and bioaccumulation
The ABC transporter P-glycoprotein (Pgp) and membrane permeability are determinant factors for absorption and disposition of xenobiotics. These studies investigated the effects of potential modulators of Pgp and/or membrane function on the disposition, bioavailability and bioaccumulation of …