Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Oxylipin"”.
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LL-37 and citrullinated LL-37: differential modulation of the oxylipin - chemokine axis
… to facilitate and regulate airway inflammation. Oxylipins are bioactive lipids that are key mediators in the process of inflammation. The human host defence peptide LL-37 enhances specific oxylipins such as prostaglandin E2 (PGE2) in fibroblasts and endothelial cells. LL-37 plays a pivotal role …
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Lipoxygenase Activity in Diatoms : A New Tool to Study the Antiproliferative Effects of Diatoms on Copepod Reproduction
… from fatty acid oxidation,our knowledge of the oxylipin metabolism in diatoms has been continuously increasing. Not only have new oxylipin compounds been identified, but it is becoming apparent thatoxylipin metabolism is highly complex and specific.<br></br><br></br>This thesis contributes to …
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Characterization of Free Oxylipins in Extracellular Vesicles from Bovine Milk
… This research aimed to characterize the free oxylipin content of EVs from bovine milk treated by pasteurization and homogenization. The hypothesis was that EVs from raw bovine milk would retain higher oxylipin levels than processed milk. Methods. Raw milk was treated by high-temperature short …
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The biogeochemistry of lipid derived infochemical signals in the ocean
The role of oxylipins in ocean biogeochemistry was investigated using microcosm amendment experiments, environmental lipidomics, and culture based studies. Oxylipins are a bioactive class of secondary metabolites produced by diatoms and other eukaryotic phytoplankton. Previous research has focused …
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The biogeochemistry of lipid derived infochemical signals in the ocean
The role of oxylipins in ocean biogeochemistry was investigated using microcosm amendment experiments, environmental lipidomics, and culture based studies. Oxylipins are a bioactive class of secondary metabolites produced by diatoms and other eukaryotic phytoplankton. Previous research has focused …
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Quorum sensing for improved production of industrially useful products from filamentous fungi
… and the oxygenated poly-unsaturated fatty acids, oxylipins, are the major signalling molecules reported in filamentous fungi. This study correlates the cell-densities of filamentous fungi to the regulation of their different physiological responses. Two fungal species have been investigated. The …
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Characterizing Oxylipins in Human Milk Extracellular Vesicles
… growth and development. There is interest in the oxylipin content of EVs that may contribute to the bioavailability of EVs. This research aims to characterize the oxylipin content of human milk EVs. Centrifugation and precipitation were used to isolate EVs from human milk (n = 20). The Folch …
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Functional Study of Lipoxygenase-mediated Resistance to Fungal Pathogens in Maize for Milk-chain Safety and in Grapevine for Sustainable Viticulture
… of polyunsaturated fatty acids (PUFAs) into oxylipins are reported in plants as a response to fungal pathogens. In this respect, lipoxygenase genes (LOXs) play a crucial role in the peroxidation of polyunsaturated fatty acids (PUFAs) into 9(S)- and 13(S)-hydroperoxides, which are further …
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Biologically active molecules from marine microalgae
… compounds belong to a class of compounds called oxylipins, that are oxygenated compounds biosynthesized from fatty acids by oxygenasecatalyzed oxygenation. Marine diatoms are able to produce the major antiproliferative oxylipins by a novel oxygenase-dependent oxidation of C16 fatty acids …
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Circadian regulation and phytohormone responses of cytochrome P450 monooxygenase genes in Arabidopsis
… P450s involved in phenylpropanoid, carotenoid, oxylipin, glucosinolate and brassinosteroid biosynthese pathways are circadian-regulated. The next phase of my research investigated the circadian rhythms of P450 genes under different phytohormone treatments including methyl jasmonate (MeJ), …
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Synthesis and application of tagging agents in mass spectrometry-based targeted metabolomics studies
… of the effect of ultramarathon exercise on oxylipin metabolites in plasma samples from the University of Kingston was carried out. In this study 2-fluoro-3-methyl pyridine (FMP) was utilised as a catalyst to add choline as a tagging agent which facilitated the sensitive detection and …
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Investigation of the roles of a membrane-bound caleosin in higher plants
… acid hydroperoxides. The latter are a class of oxylipins that are seen in fungal infection, and also play a role in various aspects of fungal spore development including sporulation and a role in cuticle synthesis. As such, Clo-3 in Arabidopsis and<br/>possibly similar caleosins in other species …
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Identification of chromosomes in hexaploid bread wheat (Triticum aestivum l.) Associated with natural or safener-induced tolerance to halauxifen-methyl
… which are a class of oxidized lipids (oxylipins) that mediate plant responses to biotic and abiotic stresses. Based on these previous findings, my current hypothesis is that safeners utilize an oxylipin-mediated signaling pathway to induce the expression of genes encoding …
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Biochemische Charakterisierung von PpoA aus Aspergillus nidulans
In der vorliegenden Arbeit wurden Psi-Faktor produzierende Oxygenasen, sogenannte Ppo-Enzyme, charakterisiert, die eine regulatorische Funktion für die Entwicklung und Mycotoxinproduktion in A. nidulans besitzen. Bioinformatische Analysen zeigten, dass Ppo-Enzyme im N-terminalen Sequenzabschnitt …