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Showing 1 to 1 of 1 for “"Oxygen-dependent radioresistance"”.
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HIF-1alpha role in oxygen-dependent radio- and chemosensitivity
Poor oxygenation (hypoxia) is a common characteristic of human solid tumours, and is associated with cell survival, metastasis and resistance to radio- and chemotherapies. Hypoxia-induced stabilisation of hypoxia-inducible factor-1α (HIF-1α) leads to changes in expression of various genes …